The cerebral hemodynamic changes measured by transcranial Doppler in normotensive, hypertensive and diabetic patients

被引：0

作者：

Nam, JH ^{[1
]}

Lee, JH ^{[1
]}

Cha, BS ^{[1
]}

Song, YD ^{[1
]}

Lim, SK ^{[1
]}

Kim, KR ^{[1
]}

Lee, HC ^{[1
]}

Huh, KB ^{[1
]}

机构：

[1] Yonsei Univ, Coll Med, Severance Hosp, Dept Internal Med,Seodaemun Ku, Seoul 120752, South Korea

来源：

RECENT ADVANCES ON THE PATHOGENESIS AND MANAGEMENT OF DIABETES MELLITUS: PROCEEDINGS OF THE 9TH KOREA-JAPAN SYMPOSIUM ON DIABETES MELLITUS, KYONGJU, KOREA, 11-12 APRIL 1997 | 1998年 / 1149卷

关键词：

diabetes; hemodynamics; hypertension; small vessel disease; transcranial Doppler;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This study was designed to demonstrate cerebral hemodynamic changes as macrovascular complication related to diabetes mellitus and hypertension. We measured mean velocities (Vm), and pulsatility indices IPI) of the middle cerebral artery (MCA) and the internal carotid artery (ICA) in 37 stroke-free normotensive diabetic patients (DM, M:F = 15:22, 33 hypertensive diabetics (DMHT, M:F = 16:17), 51 nondiabetic hypertensive (HT, M:F = 25:26, duration greater than or equal to 5 years) patients and 57 healthy controls (C, M:F = 26:31), using a three-dimensional transcranial Doppler (Transscan, EME, Uberlingen, Germany). The DM, DMHT and HT patients showed significantly higher PI of the MCA, and DMHT patients also had higher PI of the ICA than the C group. The PI of the MCA in DMHT patients was more elevated than in DM. These results showed that the cerebral hemodynamic changes in diabetes mellitus and hypertension affect pulsatility of cerebral arteries, especially small arteries. These atherosclerotic changes of cerebral arteries appear to be mon aggravated in diabetes mellitus combined with hypertension.

引用

页码：222 / 224

页数：3