Heat shock proteins and the pancreas

被引：42
作者：
Rakonczay, Z
Takács, T
Boros, I
Lonovics, J
机构：
[1] Univ Szeged, Dept Med 1, H-6701 Szeged, Hungary
[2] Hungarian Acad Sci, Biol Res Ctr, Inst Biochem, H-6701 Szeged, Hungary
来源：
JOURNAL OF CELLULAR PHYSIOLOGY | 2003年 / 195卷 / 03期
关键词：
D O I：
10.1002/jcp.10268
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Heat shock proteins (HSPs) are cytoprotective molecules that help to maintain the metabolic and structural integrity of cells. In this review, we briefly discuss the regulation and function of HSPs. The review focuses on the current knowledge of pancreatic HSP induction, the HSP level changes during acute pancreatitis, the potential effects of the pre- and co-induction of HSPs in experimental acute pancreatitis, and the mechanisms by which HSPs might mediate cellular protection. (C) 2003 Wiley-Liss, Inc.
引用
收藏
页码：383 / 391
页数：9
相关论文
共 105 条
[91]   ULTRASTRUCTURAL-STUDY OF THE EFFECTS OF STRESS ON THE PANCREAS IN RATS [J].
TAKANO, S ;
KIMURA, T ;
KAWABUCHI, M ;
YAMAGUCHI, H ;
KINJO, M ;
NAWATA, H .
PANCREAS, 1994, 9 (02) :249-257
[92]   Disruption of the HSF3 gene results in the severe reduction of heat shock gene expression and loss of thermotolerance [J].
Tanabe, M ;
Kawazoe, Y ;
Takeda, S ;
Morimoto, RI ;
Nagata, K ;
Nakai, A .
EMBO JOURNAL, 1998, 17 (06) :1750-1758
[93]   Hyperthermia induces multiple pancreatic heat shock proteins and protects against subsequent arginine-induced acute pancreatitis in rats [J].
Tashiro, M ;
Ernst, SA ;
Edwards, J ;
Williams, JA .
DIGESTION, 2002, 65 (02) :118-126
[94]   Arginine induced acute pancreatitis alters the actin cytoskeleton and increases heat shock protein expression in rat pancreatic acinar cells [J].
Tashiro, M ;
Schäfer, C ;
Yao, H ;
Ernst, SA ;
Williams, JA .
GUT, 2001, 49 (02) :241-250
[95]  
Tavaria M, 1996, CELL STRESS CHAPERON, V1, P23, DOI 10.1379/1466-1268(1996)001<0023:AHSGTT>2.3.CO
[96]  
2
[97]   PROTEIN-SYNTHESIS IN SALIVARY-GLANDS OF DROSOPHILA-MELANOGASTER - RELATION TO CHROMOSOME PUFFS [J].
TISSIERES, A ;
MITCHELL, HK ;
TRACY, UM .
JOURNAL OF MOLECULAR BIOLOGY, 1974, 84 (03) :389-+
[98]  
VELEZGRANELL CS, 1994, J CELL SCI, V107, P539
[99]   Hyperthermia induces heat shock protein expression and protection against cerulein-induced pancreatitis in rats [J].
Wagner, ACC ;
Weber, H ;
Jonas, L ;
Nizze, H ;
Strowski, M ;
Fiedler, F ;
Printz, H ;
Steffen, H ;
Goke, B .
GASTROENTEROLOGY, 1996, 111 (05) :1333-1342
[100]   SUPRAMAXIMAL SECRETAGOGUE STIMULATION ENHANCES HEAT-SHOCK PROTEIN EXPRESSION IN THE RAT PANCREAS [J].
WEBER, CK ;
GRESS, T ;
MULLERPILLASCH, F ;
LERCH, MM ;
WEIDENBACH, H ;
ADLER, G .
PANCREAS, 1995, 10 (04) :360-367
234567891011