Self-assembled peptide nanoarrays: An approach to studying protein-protein interactions

被引：105
|
作者：
Williams, Berea A. R.
Lund, Kyle
Liu, Yan
Yan, Hao
Chaput, John C. [1 ]
机构：
[1] Arizona State Univ, Dept Chem & Biochem, Biodesign Inst, Ctr BioOpt Nanotechnol, Tempe, AZ 85287 USA
[2] Arizona State Univ, Dept Chem & Biochem, Ctr Single Mol Biophys, Biodesign Inst, Tempe, AZ 85287 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 17期
关键词：
DNA; nanostructures; peptide nanoarrays; self-assembly;
D O I：
10.1002/anie.200603919
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Figure Presented) On show: High-density peptide arrays capable of displaying many different amino acid sequences at well-defined and addressable locations on the same DNA nanostructure have been produced. The strategy used relies on the genetic information encoded in the nucleic acid portion of a DNA-tagged peptide to position the amino acid sequence at a predetermined location on the array. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：3051 / 3054
页数：4
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