Persulfidation is the mechanism underlying sulfide-signaling of autophagy

被引：11

作者：

Gotor, Cecilia ^{[1
]}

Aroca, Angeles ^{[1
]}

Romero, Luis C. ^{[1
]}

机构：

[1] Univ Seville, CSIC, Inst Bioquim Vegetal & Fotosintesis, Ave Amer Vespucio 49, Seville 41092, Spain

来源：

AUTOPHAGY | 2022年 / 18卷 / 03期

关键词：

Arabidopsis; GAPDH; hydrogen sulfide; persulfidated cysteine; posttranslational modification; stress; HYDROGEN-SULFIDE;

D O I：

10.1080/15548627.2021.1936357

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In this commentary, we highlight the findings described in a recent paper regarding the mechanism of H2S regulation of macroautophagy/autophagy in mammalian cells and discuss the similarities/divergencies with plant cells. The main outcome is that the posttranslational modification of thiol groups of cysteine residues to form persulfides is a conserved molecular mechanism.

引用

收藏

页码：695 / 697

页数：3

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