Angiotensin I-converting (ACE)-inhibitory and anti-inflammatory properties of commercially available Greek yoghurt made from bovine or ovine milk: A comparative study

被引：13

作者：

Politis, Ioannis ^{[1
]}

Theodorou, Georgios ^{[1
]}

机构：

[1] Agr Univ Athens, Dept Anim Sci & Aquaculture, Iera Odos 75, GR-11855 Athens, Greece

来源：

INTERNATIONAL DAIRY JOURNAL | 2016年 / 58卷

关键词：

PEPTIDES; PCR;

D O I：

10.1016/j.idairyj.2016.01.003

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

The objective of this study was to compare the presence of peptides with angiotensin I-converting (ACE)-inhibitory and immunomodulatory activities in commercial Greek yoghurt made from bovine or ovine milk. Water soluble extracts (WSE) in yoghurts made from ovine milk exhibited higher ACE-inhibitory activity than their bovine counterparts. Similarly, ovine yoghurt WSE inhibited more effectively the expression of two pro-inflammatory genes (inducible NO synthase and cyclooxygenase-2) by ovine monocytes. Following gel filtration of WSE by Sephadex G25, one fraction exhibited only ACE-inhibitory activity, two only immune inhibitory while one possessed both activities. Thus, selected peptidic fractions mimicked the original effects observed in WSE prior to fractionation. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：46 / 49

页数：4

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