Palladium catalyzed domino reaction of 1,4-disubstituted 1,2,3-triazoles via double C-H functionalization: one-pot synthesis of triazolo[1,5-f]phenanthridines

被引：28

作者：

Kumar, Avnish ^{[1
,2
]}

Shinde, Sundar S. ^{[1
,2
]}

Tiwari, Dharmendra Kumar ^{[1
]}

Sridhar, Balasubramanian ^{[3
]}

Likhar, Pravin R. ^{[1
,2
]}

机构：

[1] CSIR Indian Inst Chem Technol, Inorgan & Phys Chem Div, Organometall Gp, Hyderabad 500007, Andhra Pradesh, India

[2] CSIR Indian Inst Chem Technol, Acad Sci & Innovat Res AcSIR, Hyderabad 500007, Andhra Pradesh, India

[3] CSIR Indian Inst Chem Technol, Xray Crystall Ctr, Hyderabad 500007, Andhra Pradesh, India

来源：

RSC ADVANCES | 2016年 / 6卷 / 49期

关键词：

FACILE SYNTHESIS; BOND FORMATION; DERIVATIVES; CONSTRUCTION; ACTIVATION; ARYLATION; ARYL; DIFUNCTIONALIZATION; ALKYLATION; ROUTE;

D O I：

10.1039/c6ra06755g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A palladium catalyzed domino coupling reaction of 1,4-disubstituted triazoles via homocondensation with a second molecule is presented. The domino couplings involve the formation of biaryl and bi(hetero)aryl bonds through a five membered carbopalladacycle intermediate. The approach provides a simple, straight forward and facile route to access triazolo[1,5-f]phenanthridines in high yields. Furthermore, the developed protocol was extended to heterocondensation in the presence of norbornene.

引用

收藏

页码：43638 / 43647

页数：10

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