The effects of dioxin on reproduction and development

被引:27
作者
Yonemoto, J [1 ]
机构
[1] Natl Inst Environm Studies, Tsukuba, Ibaraki 3050053, Japan
关键词
dioxin; TCDD; reproductive effects; developmental effects; risk assessment; breast milk;
D O I
10.2486/indhealth.38.259
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The developmental effects of dioxin are important because of the high sensitivity of mammals as well as the irreversibility and longevity of the effects. In animal experiments, exposure to dioxin during pregnancy and lactation induce various functional effects on offspring at very low doses. In humans, even if there is no exposure to dioxin after birth, there might be effects on thyroid function in infants exposed to dioxin from breast milk. In this report, low-dose developmental effects of dioxins on offspring in animal experiments and human studies were reviewed. In terms of risk assessment, methods to describe dosimetry, models to describe dose-response and approaches to express health risk are discussed.
引用
收藏
页码:259 / 268
页数:10
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