A near infrared ratiometric fluorescent probe with aggregation induced emission (AIE) characteristics for hydrazine detection in vitro and in vivo

被引:40
作者
Zhang, Tiange [1 ]
Zhu, Linlin [1 ]
Lin, Weiying [1 ,2 ]
机构
[1] Univ Jinan, Sch Chem & Chem Engn, Sch Mat Sci & Engn, Inst Fluorescent Probes Biol Imaging, Jinan 250022, Shandong, Peoples R China
[2] Guangxi Univ, Inst Opt Mat & Chem Biol, Guangxi Key Lab Electrochem Energy Mat, Sch Chem & Chem Engn, Nanning 530004, Guangxi, Peoples R China
关键词
Detection of hydrazine; Near-infrared; Ratiometric fluorescent probe; Aggregation induced emission; Zebrafish imaging; ELECTROCATALYTIC OXIDATION; METHYLHYDRAZINE; MECHANISM; WATER; GOLD;
D O I
10.1016/j.dyepig.2021.109177
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Hydrazine (N2H4) is widely used in agriculture and chemical industry because of its alkalinity and reducibility. However, inhalation of excessive hydrazine can cause extremely damage to human health. Herein, a near infrared ratiometric fluorescent probe PBT with aggregation induced emission (AIE) characteristics for hydrazine detection was reported. The probe PBT represents desirable characteristics including near-infrared (NIR), ratiometric detection, high selectivity, low detection limit (0.11 nM) as well as large Stokes shift (200 nm). Significantly, the probe PBT can be applied to detecting hydrazine vapor and imaging hydrazine in HepG(2) cells and zebrafish.
引用
收藏
页数:6
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