Maestro of the SereNADe: SLC25A51 Orchestrates Mitochondrial NAD

被引：7

作者：

Ouyang, Yeyun ^{[1
]}

Bott, Alex J. ^{[1
]}

Rutter, Jared ^{[1
,2
]}

机构：

[1] Univ Utah, Sch Med, Dept Biochem, Salt Lake City, UT 84132 USA

[2] Howard Hughes Med Inst, Chevy Chase, MD 20815 USA

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2021年 / 46卷 / 05期

关键词：

D O I：

10.1016/j.tibs.2021.02.001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recently, three groups, Girardi et al., Kory et al., and Luongo et al., inde-pendently identified solute carrier (SLC) 25A51 as the long-sought, major mitochondrial NAD+ trans-porter in mammalian cells. These studies not only deorphan an uncharacterized transporter of the SLC25A family, but also shed light on other aspects of NAD+ biology.

引用

页码：348 / 350

页数：3

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