Dendritic cells, new tools for vaccination

被引:21
作者
Colino, J [1 ]
Snapper, CM [1 ]
机构
[1] Uniformed Serv Univ Hlth Sci, Dept Pathol, Bethesda, MD 20814 USA
关键词
vaccines; immunotherapy; dendritic cells;
D O I
10.1016/S1286-4579(03)00033-9
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Our rapidly expanding knowledge of the biology of the dendritic cell (DC), a major antigen-presenting cell connecting innate and adaptive immunity, suggests new possibilities for the development of vaccines and therapeutic strategies against pathogens, through the manipulation of their function in vivo, or the injection of the DC itself, once properly instructed ex vivo. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
引用
收藏
页码:311 / 319
页数:9
相关论文
共 32 条
[1]   Dendritic cells pulsed with fungal RNA induce protective immunity to Candida albicans in hematopoietic transplantation [J].
Bacci, A ;
Montagnoli, C ;
Perruccio, K ;
Bozza, S ;
Gaziano, R ;
Pitzurra, L ;
Velardi, A ;
d'Ostiani, CF ;
Cutler, JE ;
Romani, L .
JOURNAL OF IMMUNOLOGY, 2002, 168 (06) :2904-2913
[2]   Blood dendritic cells interact with splenic marginal zone B cells to initiate T-Independent immune responses [J].
Balázs, M ;
Martin, F ;
Zhou, T ;
Kearney, JF .
IMMUNITY, 2002, 17 (03) :341-352
[3]   Immunobiology of dendritic cells [J].
Banchereau, J ;
Briere, F ;
Caux, C ;
Davoust, J ;
Lebecque, S ;
Liu, YT ;
Pulendran, B ;
Palucka, K .
ANNUAL REVIEW OF IMMUNOLOGY, 2000, 18 :767-+
[4]   Dendritic cells pulsed with intact Streptococcus pneumoniae elicit both protein- and polysaccharide-specific immunoglobulin isotype responses in vivo through distinct mechanisms [J].
Colino, J ;
Shen, Y ;
Snapper, CM .
JOURNAL OF EXPERIMENTAL MEDICINE, 2002, 195 (01) :1-13
[5]   Interaction of dendritic cells with mycobacteria: Where the action starts [J].
Demangel, C ;
Britton, WJ .
IMMUNOLOGY AND CELL BIOLOGY, 2000, 78 (04) :318-324
[6]  
Eggert AAO, 1999, CANCER RES, V59, P3340
[7]   Flt3 ligand pretreatment promotes protective immunity to Listeria monocytogenes [J].
Gregory, SH ;
Sagnimeni, AJ ;
Zurowski, NB ;
Thomson, AW .
CYTOKINE, 2001, 13 (04) :202-208
[8]   Antigen presentation and T cell stimulation by dendritic cells [J].
Guermonprez, P ;
Valladeau, J ;
Zitvogel, L ;
Théry, C ;
Amigorena, S .
ANNUAL REVIEW OF IMMUNOLOGY, 2002, 20 :621-667
[9]   Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo [J].
Hawiger, D ;
Inaba, K ;
Dorsett, Y ;
Guo, M ;
Mahnke, K ;
Rivera, M ;
Ravetch, JV ;
Steinman, RM ;
Nussenzweig, MC .
JOURNAL OF EXPERIMENTAL MEDICINE, 2001, 194 (06) :769-779
[10]  
Jarrossay D, 2001, EUR J IMMUNOL, V31, P3388, DOI 10.1002/1521-4141(200111)31:11<3388::AID-IMMU3388>3.0.CO