Flow parameters in normal left coronary artery tree. Implication to atherogenesis

被引：28
作者：
Soulis, Johannes V.
Giannoglou, George D. [1 ]
Parcharidis, George E.
Louridas, George E.
机构：
[1] Aristotle Univ Thessaloniki, AHEPA Univ Gen Hosp, Dept Cardiol, GR-54006 Thessaloniki, Greece
[2] Democritus Univ Thrace, Dept Civil Engn, GR-67100 Xanthi, Greece
来源：
COMPUTERS IN BIOLOGY AND MEDICINE | 2007年 / 37卷 / 05期
关键词：
computer modeling; haemodynamics; coronary circulation; LCA; atherosclerosis;
D O I：
10.1016/j.compbiomed.2006.06.006
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The dominant haemodynamic flow parameters of wall pressure (WP), wall shear stress (WSS), molecular viscosity and the spatial gradients: wall pressure gradient (WPG) and wall shear stress gradient (WSSG) along the normal human left coronary artery (LCA) tree are numerically analyzed in relation to atheronegenesis. The LCA tree includes the left main coronary artery, the left anterior descending branch, the left circumflex branch and their major branches. Spatial differentiation indicates that low values of WP (locally), WPG, WSS, WSSG and high molecular viscosity appear opposite flow dividers and this probably correlates to atherosclerosis localization. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：628 / 636
页数：9
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