A concise route to the highly-functionalized azetidine precursor: the enantioselective synthesis of penaresidin B

被引：14

作者：

Ding, Feiqing ^{[1
]}

William, Ronny ^{[1
]}

Kock, Si Min ^{[1
]}

Leow, Min Li ^{[1
]}

Liu, Xue-Wei ^{[1
]}

机构：

[1] Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, Singapore 637371, Singapore

来源：

CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 22期

关键词：

STEREOSELECTIVE-SYNTHESIS; ASYMMETRIC-SYNTHESIS; ALKALOIDS; MITSUNOBU;

D O I：

10.1039/c4cc09904d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient and high-yielding synthesis of penaresidin B is disclosed herein. The concise 8-step synthesis of azetidine aldehyde was devised by incorporating our novel strategy for ready access to 3-amino-2,3-dideoxysugars via regio- and stereoselective tandem hydroamination/glycosylation of glycal as the key step.

引用

页码：4639 / 4642

页数：4

共 39 条

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