Molecularly endowed hydrogel with an in silico-assisted screened peptide for highly sensitive small molecule harvesting

被引:18
作者
Di Natale, Concetta [1 ]
Celetti, Giorgia [1 ]
Scognamiglio, Pasqualina Liana [1 ]
Cosenza, Chiara [2 ]
Battista, Edmondo [2 ]
Causa, Filippo [1 ,2 ,3 ]
Netti, Paolo A. [1 ,2 ,3 ]
机构
[1] IIT, Ctr Adv Biomat Healthcare, Largo Barsanti & Matteucci 53, I-80125 Naples, Italy
[2] Univ Federico II, Interdisciplinary Res Ctr Biomat CRIB, Piazzale Tecchio 80, I-80125 Naples, Italy
[3] Univ Federico II, DICMAPI, Piazzale Tecchio 80, I-80125 Naples, Italy
关键词
MICROGELS; NANOPARTICLES; AGGREGATION; OCHRATOXIN; CHALLENGES; PROTEINS; APTAMERS; PROBES; FLUIDS;
D O I
10.1039/c8cc04943b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We present a novel method for the detection of small molecules in complex fluids based on the selection of a specific peptide for target capture and its integration into an antifouling polymeric network. Such an approach can represent a universal platform for the direct and ultra-sensitive detection of small molecules in complex media.
引用
收藏
页码:10088 / 10091
页数:4
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