Susceptibilities of methicillin-resistant Staphylococcus aureus isolates to seven biocides

被引：18
作者：
Narui, Koji
Takano, Mitsuo
Noguchi, Norihisa
Sasatsu, Masanori
机构：
[1] Tokyo Univ Pharm & Life Sci, Sch Pharm, Dept Microbiol, Hachioji, Tokyo 1920392, Japan
[2] Hokushin Gen Hosp, Dept Pharm, Nagano 3838505, Japan
来源：
BIOLOGICAL & PHARMACEUTICAL BULLETIN | 2007年 / 30卷 / 03期
关键词：
methicillin-resistant; Staplylococcus aureus; minimum bactericidal concentration; biocide; user concentrations; exposure time;
D O I：
10.1248/bpb.30.585
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Minimum bactericidal concentrations (MBCs) of seven biocides for 42 methicillin-resistant Staphylococcus aureus (MRSA) isolates at 5, 30, or 180 min, for hand scrubs or soaks, isolated in 2003 in Japan were determined. The MBC values of glutaraldehyde, povidone iodine, and ethanol were lower than the user concentrations in all exposure times. However, at 5 min exposure of sodium hypochlorite, benzalkonium chloride, alkyl-diaminoethylglycine hydrochloride, and chlorhexidine digluconate some strains showed higher MBC values than the user concentrations. These results indicated the possibility that MRSA survived under proper user concentration conditions and exposure time.
引用
收藏
页码：585 / 587
页数：3
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