Consensus and contentious statements on the use of probiotics in clinical practice: A south east Asian gastro-neuro motility association working team report

被引：23

作者：

Gwee, Kok-Ann ^{[1
,3
]}

Lee, Warren Wei-Rhen ^{[4
,5
]}

Ling, Khoon Lin ^{[6
]}

Ooi, Choon Jin ^{[6
]}

Quak, Seng Hock ^{[2
,7
]}

Dan, Yock Young ^{[4
,5
,9
]}

Siah, Kewin Tien-Ho ^{[9
]}

Huang, James Guoxian ^{[8
]}

Chua, Andrew Seng Boon ^{[11
]}

Hilmi, Ida Normiha ^{[13
]}

Ali, Raja Affendi Raja ^{[14
]}

Ong, Christina ^{[10
]}

Simadibrata, Marcellus ^{[18
]}

Abdullah, Murdani ^{[18
]}

Sollano, Jose D. ^{[19
]}

Leelakusolvong, Somchai ^{[21
]}

Gonlachanvit, Sutep ^{[22
]}

Lee, Yeong Yeh ^{[15
]}

Ricaforte-Campos, Jane D. ^{[20
]}

Yin, Yee Kian ^{[16
]}

Chong, Kuck-Meng ^{[17
]}

Wong, Chong Yuen ^{[12
]}

机构：

[1] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Med, Singapore, Singapore

[2] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Paediat Med, Singapore, Singapore

[3] Gleneagles Hosp, Annexe Block 05-37,6A Napier Rd, Singapore 258500, Singapore

[4] KK Hosp, Dept Paediat Med, Camden Med Ctr, Singapore, Singapore

[5] KK Hosp, Dept Paediat Med, Serv Endocrinol, Singapore, Singapore

[6] Gen Hosp, Dept Gastroenterol & Hepatol, Singapore, Singapore

[7] Duke NUS Med Sch, Singapore, Singapore

[8] Khoo Teck Puat Natl Univ, Childrens Med Inst, Singapore, Singapore

[9] Natl Univ Hlth Syst, Div Gastroenterol & Hepatol, Singapore, Singapore

[10] KK Womens & Childrens Hosp, Nutr & Dietet, Singapore, Singapore

[11] Ipoh Gastro Ctr, Ipoh, Malaysia

[12] Hosp Fatimah, Ipoh, Malaysia

[13] Univ Malaya, Dept Med, Div Gastroenterol & Hepatol, Kuala Lumpur, Malaysia

[14] Natl Univ Malaysia, Med Ctr, Dept Med, Unit Gastroenterol & Hepatol, Kuala Lumpur, Malaysia

[15] Univ Sci Malaysia, Sch Med Sci, Kota Baharu, Kelantan, Malaysia

[16] Klin Pakar Y&C, Menglembu, Malaysia

[17] Klnic Chong, Slim River, Perak, Malaysia

[18] Univ Indonesia, Cipto Mangunkusumo Hosp, Fac Med, Div Gastroenterol,Dept Internal Med, Jakarta, Indonesia

[19] Univ Santo Tomas Hosp, Gastroenterol Sect, Manila, Philippines

[20] Med Ctr Manila, Manila, Philippines

[21] Mahidol Univ, Siriraj Hosp, Dept Internal Med, Bangkok, Thailand

[22] Chulalongkorn Univ, Fac Med, Dept Med, GI Motil Res Unit,Div Gastroenterol, Bangkok, Thailand

来源：

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | 2018年 / 33卷 / 10期

关键词：

Asia; childhood; gastrointestinal; liver; obesity; probiotics; IRRITABLE-BOWEL-SYNDROME; LACTOBACILLUS-RHAMNOSUS GG; FECAL MICROBIOTA TRANSPLANTATION; ANTIBIOTIC-ASSOCIATED DIARRHEA; TREATING ACUTE GASTROENTERITIS; RANDOMIZED DOUBLE-BLIND; MAINTAINING REMISSION; MICROBIOLOGICAL EVALUATION; SACCHAROMYCES-BOULARDII; HEPATIC-ENCEPHALOPATHY;

D O I：

10.1111/jgh.14268

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The concept of consuming microorganisms in the treatment of a medical condition and in health maintenance has gained much attraction, giving rise to an abundance of medical claims and of health supplements. This study identified relevant clinical questions on the therapeutic use of probiotics and reviewed the literature in irritable bowel syndrome, inflammatory bowel disease, impaired intestinal immunity, liver disease, intestinal infections, and common childhood digestive disorders. Statements were developed to address these clinical questions. A panel of experienced clinicians was tasked to critically evaluate and debate the available data. Both consensus and contentious statements are presented to provide to clinicians a perspective on the potential of probiotics and importantly their limitations.

引用

页码：1707 / 1716

页数：10

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