The Association between ADHD and the Severity of COVID-19 Infection

被引：39

作者：

Merzon, Eugene ^{[1
,2
]}

Weiss, Margaret D. ^{[5
]}

Cortese, Samuele ^{[6
,7
,8
,9
,10
]}

Rotem, Ann ^{[11
]}

Schneider, Tzipporah ^{[12
]}

Craig, Stephanie G. ^{[13
]}

Vinker, Shlomo ^{[1
,2
]}

Golan Cohen, Avivit ^{[1
,2
]}

Green, Ilan ^{[1
,2
]}

Ashkenazi, Shai ^{[14
,15
]}

Weizman, Abraham ^{[3
,11
]}

Manor, Iris ^{[4
,11
]}

机构：

[1] Leumit HMO, Tel Aviv, Israel

[2] Tel Aviv Univ, Sackler Sch Med, Dept Family Med, Tel Aviv, Israel

[3] Tel Aviv Univ, Sackler Sch Med, Tel Aviv, Israel

[4] Tel Aviv Univ, Sackler Sch Med, Psychiat, Tel Aviv, Israel

[5] Cambridge Hlth Alliance, Child Psychiat, Cambridge, MA 3 USA

[6] Univ Southampton, Fac Environm & Life Sci, Sch Psychol, Ctr Innovat Mental Hlth, Southampton, Hants, England

[7] Univ Southampton, Fac Med, Clin & Expt Sci CNS & Psychiat, Southampton, Hants, England

[8] Solent NHS Trust, Southampton, Hants, England

[9] New York Univ, NYU Langone, Ctr Child Study, Hassenfeld Childrens Hosp, New York, NY USA

[10] Univ Nottingham, Sch Med, Div Psychiat & Appl Psychol, Nottingham, England

[11] Geha Mental Hlth Ctr, ADHD Unit, 1 Helsinki Rd, IL-49100 Petah Tiqwa, Israel

[12] Clalit Hlth Serv, Bnei Braq, Israel

[13] York Univ, Toronto, ON, Canada

[14] Ariel Univ, Med, Ariel, Israel

[15] Ariel Univ, Adelson Sch Med, Ariel, Israel

来源：

JOURNAL OF ATTENTION DISORDERS | 2022年 / 26卷 / 04期

关键词：

ADHD; COVID-19; symptom severity; referral to hospitalization; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; OLDER-ADULTS; PREVALENCE; MORTALITY;

D O I：

10.1177/10870547211003659

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Objective: Patients with ADHD are at increased risk of acquiring COVID-19. The present study assessed the possibility that ADHD also increases the risk of severe COVID-19 infection. Method: We assessed 1,870 COVID-19 positive patients, aged 5 to 60 years, registered in the database of Leumit Health Services (LHS, Israel), February to -June 2020, of whom 231 with ADHD. Logistic regression analysis models evaluated the association between ADHD and the dependent variables of being symptomatic/referral to hospitalization, controlling for demographic and medical variables. Results: Age, male sex, and BMI were confirmed to be significant risk factors for increased COVID-19 severity. ADHD was found to be associated with increased severity of COVID-19 symptoms (OR = 1.81, 95% CI [1.29, 2.52], p < .05) and referral to hospitalization (OR =1.93, 95% CI [1.06, 3.51], p = .03). Conclusion: ADHD is associated with poorer outcomes in COVID-19 infection.

引用

页码：491 / 501

页数：11

共 35 条

[1] Population-Based Estimates of Chronic Conditions Affecting Risk for Complications from Coronavirus Disease, United States [J].

Adams, Mary L. ;

Katz, David L. ;

Grandpre, Joseph .

EMERGING INFECTIOUS DISEASES, 2020, 26 (08) :1831-1833

[2] Racial Disparities-Associated COVID-19 Mortality among Minority Populations in the US [J].

Alcendor, Donald J. .

JOURNAL OF CLINICAL MEDICINE, 2020, 9 (08) :1-17

[3] Diagnosis and Treatment of Attention-Deficit/Hyperactivity Disorder in Preschool-Aged Children [J].

Childress, Ann C. ;

Stark, Jeffrey G. .

JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 2018, 28 (09) :606-614

[4] Association between mental disorders and somatic conditions: protocol for an umbrella review [J].

Cortese, Samuele ;

Solmi, Marco ;

Arrondo, Gonzalo ;

Cipriani, Andrea ;

Fusar-Poli, Paolo ;

Larsson, Henrik ;

Correll, Christoph .

EVIDENCE-BASED MENTAL HEALTH, 2020, 23 (04) :135-139

[5] Association between inflammatory cytokines and ADHD symptoms in children and adolescents with obesity: A pilot study [J].

Cortese, Samuele ;

Angriman, Marco ;

Comencini, Erika ;

Vincenzi, Brenda ;

Maffeis, Claudio .

PSYCHIATRY RESEARCH, 2019, 278 :7-11

[6] Twenty years of research on attention-deficit/hyperactivity disorder (ADHD): looking back, looking forward [J].

Cortese, Samuele ;

Coghill, David .

EVIDENCE-BASED MENTAL HEALTH, 2018, 21 (04) :173-176

[7] Association between attention deficit hyperactivity disorder and asthma: a systematic review and meta-analysis and a Swedish population-based study [J].

Cortese, Samuele ;

Sun, Shihua ;

Zhang, Junhua ;

Sharma, Esha ;

Chang, Zheng ;

Kuja-Halkola, Ralf ;

Almqvist, Catarina ;

Larsson, Henrik ;

Faraone, Stephen V. .

LANCET PSYCHIATRY, 2018, 5 (09) :717-726

[8] Association Between ADHD and Obesity: A Systematic Review and Meta-Analysis [J].

Cortese, Samuele ;

Moreira-Maia, Carlos Renato ;

St Fleur, Diane ;

Morcillo-Penalver, Carmen ;

Rohde, Luis Augusto ;

Faraone, Stephen V. .

AMERICAN JOURNAL OF PSYCHIATRY, 2016, 173 (01) :34-43

[9] Sleep in Children With Attention-Deficit/Hyperactivity Disorder: Meta-Analysis of Subjective and Objective Studies [J].

Cortese, Samuele ;

Faraone, Stephen V. ;

Konofal, Eric ;

Lecendreux, Michel .

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 2009, 48 (09) :894-908

[10] The association of unipolar depression with thirty-day mortality after hospitalization for infection: A population-based cohort study in Denmark [J].

Davydow, Dimitry S. ;

Ribe, Anette Riisgaard ;

Pedersen, Henrik Sondergaard ;

Vestergaard, Mogens ;

Fenger-Gron, Morten .

JOURNAL OF PSYCHOSOMATIC RESEARCH, 2016, 89 :32-38

← 1 2 3 4 →