Direct Conversion of Arylamines to Pinacol Boronates: A Metal-Free Borylation Process

被引：209
作者：
Mo, Fanyang [1 ,2 ]
Jiang, Yubo [3 ]
Qiu, Di [1 ,2 ]
Zhang, Yan [1 ,2 ]
Wang, Jianbo [1 ,2 ]
机构：
[1] Peking Univ, Coll Chem, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China
[2] Peking Univ, Coll Chem, Key Lab Bioorgan Chem & Mol Engn, Minist Educ, Beijing 100871, Peoples R China
[3] Tongji Univ, Dept Chem, Shanghai 200092, Peoples R China
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 10期
关键词：
aryl boronates; borylation; cross-coupling; diazo compounds; Sandmeyer reaction; PALLADIUM-CATALYZED BORYLATION; CROSS-COUPLING REACTION; C-H BORYLATION; ROOM-TEMPERATURE REACTIONS; ONE-POT SYNTHESIS; ORGANOBORON COMPOUNDS; ARYL HALIDES; AROMATIC BORYLATION; ARYLBORONIC ESTERS; IRIDIUM COMPLEXES;
D O I：
10.1002/anie.200905824
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Leave the metal out: Arylboronates are produced In moderate to good yields by direct borylation of readily available aryl amines (see scheme). The reaction can be carried out under air at room temperature and transition-metal catalysis is not required. The boronate products can be used without purification in SuzukiMiyaura cross-coupling reactions. Chemical equation representation © 2010 Wiley-VCH Verlag GmbH & Co. KGaA www.angewandte.org.
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收藏
页码：1846 / 1849
页数：4
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