Growth hormone treatment of short children born small for gestational age

被引:0
作者
Czernichow, P
机构
关键词
growth hormone; intrauterine growth retardation; short stature; bone maturation; metabolism;
D O I
暂无
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The administration of growth hormone (GH) for a short period to short children born small for gestational age increases growth velocity. Children receiving 2-3 times the replacement dose gained nearly 2.0 SDS in height over a 3-year treatment period. This treatment is well tolerated, without significant side-effects. Further studies of the growth rate following cessation of GH treatment will reveal whether the gain in height is maintained, and whether the final height prediction is improved.
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页码:213 / 215
页数:3
相关论文
共 12 条
[1]   Persistent short stature in children with intrauterine growth retardation: Use of growth hormone treatment [J].
Albanese, A ;
Stanhope, R .
HORMONE RESEARCH, 1997, 48 :63-66
[2]   FETAL NUTRITION AND CARDIOVASCULAR-DISEASE IN ADULT LIFE [J].
BARKER, DJP ;
GLUCKMAN, PD ;
GODFREY, KM ;
HARDING, JE ;
OWENS, JA ;
ROBINSON, JS .
LANCET, 1993, 341 (8850) :938-941
[3]   DOSE-DEPENDENT CATCH-UP GROWTH AFTER 2 YEARS OF GROWTH-HORMONE TREATMENT IN INTRAUTERINE GROWTH-RETARDED CHILDREN [J].
CHATELAIN, P ;
JOB, JC ;
BLANCHARD, J ;
DUCRET, JP ;
OLIVIER, M ;
SAGNARD, L ;
VANDERSCHUERENLODEWEYCKX, M .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1994, 78 (06) :1454-1460
[4]   EFFECTS OF GROWTH-HORMONE THERAPY IN PREPUBERTAL CHILDREN WITH SHORT STATURE SECONDARY TO INTRAUTERINE GROWTH-RETARDATION [J].
CHAUSSAIN, JL ;
COLLE, M ;
LANDIER, F .
ACTA PAEDIATRICA, 1994, 83 :74-76
[5]   GROWTH-HORMONE TREATMENT IN GROWTH HORMONE-DEFICIENT ADULTS .1. EFFECTS ON MUSCLE MASS AND STRENGTH [J].
CUNEO, RC ;
SALOMON, F ;
WILES, CM ;
HESP, R ;
SONKSEN, PH .
JOURNAL OF APPLIED PHYSIOLOGY, 1991, 70 (02) :688-694
[6]   High-dose growth hormone treatment of short children born small for gestational age [J].
deZegher, F ;
Maes, M ;
Gargosky, SE ;
Heinrichs, C ;
DuCaju, MVL ;
Thiry, G ;
DeSchepper, J ;
Craen, M ;
Breysem, L ;
Lofstrom, A ;
Jonsson, P ;
Bourguignon, JP ;
Malvaux, P ;
Rosenfeld, RG .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1996, 81 (05) :1887-1892
[7]  
FJELLESTADPAULS.A, 1997, IN PRESS ACTA PAEDIA
[8]  
JORGENSEN JOL, 1991, ACTA ENDOCRINOL-COP, V125, P449
[9]  
JORGENSEN JOL, 1989, LANCET, V1, P1221
[10]   MAGNETIC-RESONANCE-IMAGING EVALUATION OF ADIPOSE-TISSUE AND MUSCLE-TISSUE MASS IN CHILDREN WITH GROWTH-HORMONE (GH) DEFICIENCY, TURNERS-SYNDROME, AND INTRAUTERINE GROWTH-RETARDATION DURING THE FIRST YEAR OF TREATMENT WITH GH [J].
LEGER, J ;
CAREL, C ;
LEGRAND, I ;
PAULSEN, A ;
HASSAN, M ;
CZERNICHOW, P .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1994, 78 (04) :904-909