Efficacy of a Group-Based Dietary Intervention for Limiting Gestational Weight Gain among Obese Women: A Randomized Trial

被引:99
作者
Vesco, Kimberly K. [1 ,2 ]
Karanja, Njeri [1 ]
King, Janet C. [3 ]
Gillman, Matthew W. [4 ]
Leo, Michael C. [1 ]
Perrin, Nancy [1 ]
McEvoy, Cindy T. [5 ]
Eckhardt, Cara L. [6 ]
Smith, K. Sabina [1 ]
Stevens, Victor J. [1 ]
机构
[1] Kaiser Permanente, Ctr Hlth Res, Portland, OR 97227 USA
[2] Kaiser Permanente, Dept Obstet & Gynecol, Portland, OR 97232 USA
[3] Childrens Hosp Oakland, Res Inst, Oakland, CA 94609 USA
[4] Harvard Univ, Sch Med, Harvard Pilgrim Hlth Care Inst, Obes Prevent Program, Boston, MA 02215 USA
[5] Oregon Hlth & Sci Univ, Portland, OR 97239 USA
[6] Portland State Univ, Sch Community Hlth, Portland, OR 97201 USA
关键词
LIFE-STYLE INTERVENTION; PREGNANT-WOMEN; PHYSICAL-ACTIVITY; OUTCOMES; MAINTENANCE;
D O I
10.1002/oby.20831
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: Observational studies suggest that minimal gestational weight gain (GWG) may optimize pregnancy outcomes for obese women. This trial tested the efficacy of a group-based weight management intervention for limiting GWG among obese women. Methods: One hundred and fourteen obese women (BMI [mean +/- SD] 36.7 +/- 4.9 kg/m(2)) were randomized between 7 and 21 weeks' (14.9 +/- 2.6) gestation to intervention (n = 56) or usual care control conditions (n = 58). The intervention included individualized calorie goals, advice to maintain weight within 3% of randomization and follow the Dietary Approaches to Stop Hypertension dietary pattern without sodium restriction, and attendance at weekly group meetings until delivery. Control participants received one-time dietary advice. Our three main outcomes were maternal weight change from randomization to 2 weeks postpartum and from randomization to 34 weeks gestation, and newborn large-for-gestational age (birth weight >90th percentile, LGA). Results: Intervention participants gained less weight from randomization to 34 weeks gestation (5.0 vs. 8.4 kg, mean difference = -3.4 kg, 95% CI [-5.1-1.8]), and from randomization to 2 weeks postpartum (-2.6 vs. +1.2 kg, mean difference = -3.8 kg, 95% CI [-5.9-1.7]). They also had a lower proportion of LGA babies (9 vs. 26%, odds ratio = 0.28, 95% CI [0.09-0.84]). Conclusions: The intervention resulted in lower GWG and lower prevalence of LGA newborns.
引用
收藏
页码:1989 / 1996
页数:8
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