Metabolic syndrome and liver transplantation: A review and guide to management

被引:161
作者
Watt, Kymberly D. S. [1 ]
Charlton, Michael R. [1 ]
机构
[1] Mayo Clin, Mayo Clin Transplant Ctr, Dept Gastroenterol & Hepatol, Mayo Clin & Fdn, Rochester, MN 55905 USA
关键词
Metabolic syndrome; Obesity; BMI; Liver disease; Post-liver transplant; ONSET DIABETES-MELLITUS; ADIPOSE-TISSUE COMPARTMENTS; CORONARY-ARTERY-DISEASE; SEVERELY OBESE-PATIENTS; LONG-TERM SURVIVAL; C VIRUS-INFECTION; FATTY LIVER; HEPATITIS-C; INSULIN-RESISTANCE; RISK-FACTORS;
D O I
10.1016/j.jhep.2010.01.040
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Metabolic syndrome is common among liver transplant recipients before and after transplantation. The components of metabolic syndrome are often exacerbated in the post-transplant period by transplant specific factors, such as immunosuppression, and are strong predictors of patient morbidity and mortality. Many aspects of the metabolic syndrome are modifiable. Early recognition, prevention and treatment of post-transplant hypertension, obesity, dyslipidemia and diabetes may impact long-term post-transplant survival. Further study into the prevention and management of these issues in the transplant patient are needed. (C) 2010 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:199 / 206
页数:8
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