Recent advances in liver transplantation for cancer: The future of transplant oncology

被引：23

作者：

Abreu, Phillipe ^{[1
]}

Gorgen, Andre ^{[1
]}

Oldani, Graziano ^{[1
]}

Hibi, Taizo ^{[2
]}

Sapisochin, Gonzalo ^{[1
]}

机构：

[1] Univ Toronto, Multiorgan Transplant Program, Toronto Gen Hosp, Div Gen Surg,Univ Hlth Network, Toronto, ON, Canada

[2] Kumamoto Univ, Dept Pediat Surg & Transplantat, Grad Sch Med Sci, Kumamoto, Japan

来源：

JHEP REPORTS | 2019年 / 1卷 / 05期

关键词：

Liver transplant; Oncology; Hepatocellular Carcinoma; Cholangiocarcinoma; Colorectal Liver Metastasis; Neuroendocrine Tumours; Hepatic Epithelioid Hemangioendothelioma; HEPATOCELLULAR-CARCINOMA RECURRENCE; HEPATIC EPITHELIOID HEMANGIOENDOTHELIOMA; ALPHA-FETOPROTEIN; NEUROENDOCRINE TUMORS; INTRAHEPATIC CHOLANGIOCARCINOMA; PERIHILAR CHOLANGIOCARCINOMA; LOCOREGIONAL THERAPY; SELECTION CRITERIA; MILAN CRITERIA; METASTASES;

D O I：

10.1016/j.jhepr.2019.07.004

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Liver transplantation is widely indicated as a curative treatment for selected patients with hepatocellular carcinoma. However, with recent therapeutic advances, as well as efforts to increase the donor pool, liver transplantation has been carefully expanded to patients with other primary or secondary malignancies in the liver. Cholangiocarcinoma, colorectal and neuroendocrine liver metastases, and hepatic epithelioid haemangioendothelioma are amongst the most relevant new indications. In this review we discuss the fundamental concepts of this ambitious undertaking, as well as the newest indications for liver transplantation, with a special focus on future perspectives within the recently established concept of transplant oncology. (C) 2019 The Author(s). Published by Elsevier B.V. on behalf of European Association for the Study of the Liver (EASL).

引用

页码：377 / 391

页数：15

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