One-pot, two-step synthesis of substituted triazoloquinoxalinone starting from 3-hydrazineylquinoxalin-2(1H)-one

被引：3
|
作者：
Patil, Vikas S. [1 ]
Yadavalli, Subba Rao [1 ]
Merugu, Ramchander [2 ]
Swamy, S. J. [3 ]
Devunuri, Nagaraju [1 ]
机构：
[1] Vignans Fdn Sci Technol & Res VFSTR Deemed Univ, Div Chem, Dept Sci & Humanities, Guntur 522213, Andhra Pradesh, India
[2] Mahatma Gandhi Univ, Dept Bio Chem, Nalgonda, India
[3] Kakatiya Univ, Dept Chem, Warangal, Andhra Pradesh, India
来源：
SYNTHETIC COMMUNICATIONS | 2021年 / 51卷 / 13期
关键词：
Hydrazine; ferric chloride; 3-hydrazineylquinoxalin-2(1H)-one; DERIVATIVES; MELANOMA; DESIGN;
D O I：
10.1080/00397911.2021.1918171
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient one-pot two-step synthesis of substituted-triazolo[4,3-a]quinoxalin-4(5H)-one has been developed. The 3-hydrazineylquinoxalin-2(1H)-one reacts with respective aldehyde to afford the individual hydrazineylidene intermediate which undergoes oxidative cyclization in the presence of ferric chloride hexahydrate (FeCl3.6H(2)O) to affords various substituted- triazolo[4,3-a]quinoxalin-4(5H)-one in good to excellent yields.
引用
收藏
页码：1994 / 2000
页数：7
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