Hemochromatosis Gene (HFE) Mutations and Cancer Risk: Expanding the Clinical Manifestations of Hereditary Iron Overload

被引：35
作者：
Fargion, Silvia [1 ]
Valenti, Luca [2 ]
Fracanzani, Anna Ludovica [2 ]
机构：
[1] Univ Milan, Dept Internal Med, UO Med Interna 1B, Fdn Osped Policlin Mangiagalli Regina Elena IRCCS, I-20122 Milan, Italy
[2] Univ Milan, Osped Policlin IRCCS, Dept Internal Med, Milan, Italy
来源：
HEPATOLOGY | 2010年 / 51卷 / 04期
关键词：
COLORECTAL-CANCER; DISEASE; BREAST;
D O I：
10.1002/hep.23541
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：1119 / 1121
页数：3
相关论文
共 18 条
  • [1] Prognostic impact of pre-transplantation transfusion history and secondary iron overload in patients with myelodysplastic syndrome undergoing allogeneic stem cell transplantation: a GITMO study
    Alessandrino, Emilio Paolo
    Della Porta, Matteo Giovanni
    Bacigalupo, Andrea
    Malcovati, Luca
    Angelucci, Emanuele
    Van Lint, Maria Teresa
    Falda, Michele
    Onida, Francesco
    Bernardi, Massimo
    Guidi, Stefano
    Lucarelli, Barbarella
    Rambaldi, Alessandro
    Cerretti, Raffaella
    Marenco, Paola
    Pioltelli, Pietro
    Pascutto, Cristiana
    Oneto, Rosi
    Pirolini, Laura
    Fanin, Renato
    Bosi, Alberto
    [J]. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2010, 95 (03): : 476 - 484
  • [2] Iron-overload-related disease in HFE hereditary hemochromatosis
    Allen, Katrina J.
    Gurrin, Lyle C.
    Constantine, Clare C.
    Osborne, Nicholas J.
    Delatycki, Martin B.
    Nicoll, Amanda J.
    McLaren, Christine E.
    Bahlo, Melanie
    Nisselle, Amy E.
    Vulpe, Chris D.
    Anderson, Gregory J.
    Southey, Melissa C.
    Giles, Graham G.
    English, Dallas R.
    Hopper, John L.
    Olynyk, John K.
    Powell, Lawrie W.
    Gertig, Dorota M.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (03) : 221 - 230
  • [3] Prognostic impact of elevated pretransplantation serum ferritin in patients undergoing myeloablative stem cell transplantation
    Armand, Philippe
    Kim, Haesook T.
    Cutler, Corey S.
    Ho, Vincent T.
    Koreth, John
    Alyea, Edwin P.
    Soiffer, Robert J.
    Antin, Joseph H.
    [J]. BLOOD, 2007, 109 (10) : 4586 - 4588
  • [4] Iron-Dependent Regulation of MDM2 Influences p53 Activity and Hepatic Carcinogenesis
    Dongiovanni, Paola
    Fracanzani, Anna Ludovica
    Cairo, Gaetano
    Megazzini, Chiara Paola
    Gatti, Stefano
    Rametta, Raffaela
    Fargion, Silvia
    Valenti, Luca
    [J]. AMERICAN JOURNAL OF PATHOLOGY, 2010, 176 (02) : 1006 - 1017
  • [5] Cancer as a ferrotoxic disease:: Are we getting hard stainless evidence?
    Edgren, Gustaf
    Nyren, Olof
    Melbye, Mads
    [J]. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2008, 100 (14): : 976 - 977
  • [6] Donation frequency, iron loss, and risk of cancer among blood donors
    Edgren, Gustaf
    Reilly, Marie
    Hjalgrim, Henrik
    Tran, Trung Nam
    Rostgaard, Klaus
    Adami, Johanna
    Titlestad, Kjell
    Shanwell, Agneta
    Melbye, Mads
    Nyren, Olof
    [J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2008, 100 (08) : 572 - 579
  • [7] Cancer risk in patients with hereditary hemochromatosis and in their first-degree relatives
    Elmberg, M
    Hultcrantz, R
    Ekbom, A
    Brandt, L
    Olsson, S
    Olsson, R
    Lindgren, S
    Lööf, L
    Stål, P
    Wallerstedt, S
    Almer, S
    Sandberg-Gertzén, H
    Askling, J
    [J]. GASTROENTEROLOGY, 2003, 125 (06) : 1733 - 1741
  • [8] Increased cancer risk in a cohort of 230 patients with hereditary hemochromatosis in comparison to matched control patients with non-iron-related chronic liver disease
    Fracanzani, AL
    Conte, D
    Fraquelli, M
    Taioli, E
    Mattioli, M
    Losco, A
    Fargion, S
    [J]. HEPATOLOGY, 2001, 33 (03) : 647 - 651
  • [9] The Natural History of Serum Iron Indices for HFE C282Y Homozygosity Associated With Hereditary Hemochromatosis
    Gurrin, Lyle C.
    Osborne, Nicholas J.
    Constantine, Clare C.
    McLaren, Christine E.
    English, Dallas R.
    Gertig, Dorota M.
    Delatycki, Martin B.
    Southey, Melissa C.
    Hopper, John L.
    Giles, Graham G.
    Anderson, Gregory J.
    Olynyk, John K.
    Powell, Laurie W.
    Allen, Katrina J.
    [J]. GASTROENTEROLOGY, 2008, 135 (06) : 1945 - 1952
  • [10] HFE C282Y Homozygotes Are at Increased Risk of Breast and Colorectal Cancer
    Osborne, Nicholas J.
    Gurrin, Lyle C.
    Allen, Katrina J.
    Constantine, Clare C.
    Delatycki, Martin B.
    McLaren, Christine E.
    Gertig, Dorota M.
    Anderson, Gregory J.
    Southey, Melissa C.
    Olynyk, John K.
    Powell, Lawrie W.
    Hopper, John L.
    Giles, Graham G.
    English, Dallas R.
    [J]. HEPATOLOGY, 2010, 51 (04) : 1311 - 1318
12