Clinical and Molecular Characterization of Invasive Heteroresistant Vancomycin-Intermediate Staphylococcus aureus Infections in Korean Hospitals

被引:12
|
作者
Kim, Eu Suk [1 ,2 ]
Bae, In-Gyu [3 ]
Cho, Jeong Eun [1 ]
Choi, Yun Jung [1 ]
Kim, Il-Hwan [4 ]
Kang, Gi-Su [4 ]
Sin, Hye-yun [1 ]
Song, Kyoung-Ho [1 ,2 ]
Park, Chulmin [5 ]
Lee, Dong-Gun [5 ,6 ]
Kim, Moonsuk [1 ,2 ]
Park, Kyoung Un [7 ]
Kim, Hong Bin [1 ,2 ]
机构
[1] Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Songnam, South Korea
[2] Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul 151, South Korea
[3] Gyeongsang Natl Univ, Sch Med, Dept Internal Med, Jinju, South Korea
[4] KCDC, Korea Natl Inst Hlth, Ctr Infect Dis, Div Antimicrobial Resistance, Cheongju, South Korea
[5] Catholic Univ Korea, Vaccine Bio Res Inst, Seoul, South Korea
[6] Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul, South Korea
[7] Seoul Natl Univ, Coll Med, Dept Lab Med, Seoul, South Korea
关键词
METHICILLIN-RESISTANT; S.-AUREUS; FEATURES; BACTEREMIA; OUTCOMES; STRAINS;
D O I
10.1128/JCM.02595-15
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Invasive heteroresistant vancomycin-intermediate Staphylococcus aureus (h-VISA) isolates were identified and characterized in 10 Korean hospitals from July 2009 to June 2011. The prevalence of h-VISA infections was 3.3% (42/1,289). Most (41/42) were health care-associated infections caused by strains belonging to sequence type 5. Cases of persistent bacteremia were frequent (17/42), and 30-day mortality was high (16/40).
引用
收藏
页码:760 / 763
页数:4
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