Rhodium(III)-catalyzed C-H alkynylation of azomethine ylides under mild conditions

被引：39

作者：

Zhang, Xueyun ^{[1
,2
]}

Qi, Zisong ^{[2
]}

Gao, Jian ^{[1
]}

Li, Xingwei ^{[2
]}

机构：

[1] Qilu Univ Technol, Sch Chem & Pharmaceut Engn, Jinan 250353, Peoples R China

[2] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2014年 / 12卷 / 46期

关键词：

CATALYZED DIRECT ALKYNYLATION; TERMINAL ALKYNES; BOND FORMATION; GOLD; ACTIVATION; CASCADE; 2-ALKYNYLBENZALDEHYDE; FUNCTIONALIZATION; ISOQUINOLINES; ALKENES;

D O I：

10.1039/c4ob01596g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Rh(III)-catalyzed efficient C-H alkynylation of azomethine imines with alkynylated hypervalent iodine is developed under mild conditions. A broad scope of azomethine imines and alkyne substrates is established. The azomethine acts as a masked aldehyde and circumvents its poor directing effect.

引用

页码：9329 / 9332

页数：4

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