The BioCyc collection of microbial genomes and metabolic pathways

被引:570
作者
Karp, Peter D. [1 ]
Billington, Richard [2 ]
Caspi, Ron [2 ]
Fulcher, Carol A. [2 ]
Latendresse, Mario [2 ]
Kothari, Anamika [2 ]
Keseler, Ingrid M. [2 ]
Krummenacker, Markus [2 ]
Midford, Peter E. [2 ]
Ong, Quang [2 ]
Ong, Wai Kit [3 ]
Paley, Suzanne M. [2 ]
Subhraveti, Pallavi [3 ]
机构
[1] SRI Bioinformat Res Grp BRG, Menlo Pk, CA USA
[2] SRI Int, Menlo Pk, CA USA
[3] BRG, Menlo Pk, CA USA
基金
美国国家卫生研究院;
关键词
genome databases; microbial genome databases; metabolic pathway databases; DATABASE; PREDICTION; RESOURCE;
D O I
10.1093/bib/bbx085
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
BioCyc.org is a microbial genome Web portal that combines thousands of genomes with additional information inferred by computer programs, imported from other databases and curated from the biomedical literature by biologist curators. BioCyc also provides an extensive range of query tools, visualization services and analysis software. Recent advances in BioCyc include an expansion in the content of BioCyc in terms of both the number of genomes and the types of information available for each genome; an expansion in the amount of curated content within BioCyc; and new developments in the BioCyc software tools including redesigned gene/protein pages and metabolite pages; new search tools; a new sequence-alignment tool; a new tool for visualizing groups of related metabolic pathways; and a facility called SmartTables, which enables biologists to perform analyses that previously would have required a programmer's assistance.
引用
收藏
页码:1085 / 1093
页数:9
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