A novel synthesis of pyridine-2(1H)-thione, pyrazolo[3,4-b]pyridine, pyrido[2′,3′:3,4]pyrazolo[1,5-a]pyrimidine, thieno[2,3-b]pyrdine, and pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidine derivatives containing a naphthyl moiety

被引：14

作者：

Fattah, Azza M. Abdel

Elneairy, Mohamed A. A. ^{[1
]}

Gad-Elkareem, Mohamed A. M.

机构：

[1] Cairo Univ, Fac Sci, Dept Chem, Giza 12613, Egypt

[2] Al Azhar Univ, Dept Chem, Assiut Branch, Assiut, Egypt

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2007年 / 182卷 / 06期

关键词：

pyridine-2(1H)-thiones; pyrido[2 ',3 ': 3,4]pyrazolo-[1,5-a]pyrimidine; pyrido[3,2 : 4,5]thieno[3,2-d]pyrimidine; thieno[2,3-b]pyridine;

D O I：

10.1080/10426500601160991

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

6-Amino-4-naphthyl-2-thioxo-1,2-dihydropyridine-3,5-dicarbonitriles 3a,b were synthesized from the reaction of naphthaldehydes 1a,b and cyanothioacetamide (2). Compounds 3a,b were taken as starting materials for the synthesis of pyrazolo[3,4-b] pyridine 7a,b, and 8a, Pyrido-[2',3':3,4]pyrazolo[1,5-a]pyrimidine 9a, b; thieno[2,3-b] pyridine 16a-d, 18a,b, 21a-d, 24a,b, and 25a; and pyrido[3',2':4,5] thieno[3,2-d] pyrimidine 17a,b derivatives through their reactions with the corresponding reagents. All structures of the newly synthesized heterocyclic compounds were established on the basis of IR, H-1 NMR, C-13 NMR, mass spectra, and elemental analyses.

引用

页码：1351 / 1364

页数：14

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