NLRP3 Inflammasome: A New Promising Therapeutic Target to Treat Heart Failure

被引:14
作者
del Buono, Marco G. [1 ,2 ]
Crea, Filippo [1 ,2 ]
Versaci, Francesco [3 ]
Biondi-Zoccai, Giuseppe [4 ,5 ]
机构
[1] Univ Cattolica Sacro Cuore, Dept Cardiovasc & Pneumol Sci, Rome, Italy
[2] Policlin Univ A Gemelli IRCCS, Dept Cardiovasc Sci, Rome, Italy
[3] Osped Santa Maria Goretti, UOC UTIC Emodinam & Cardiol, Latina, Italy
[4] Sapienza Univ Rome, Dept Med Surg Sci & Biotechnol, Corso Repubbl 79, I-04100 Latina, Italy
[5] Mediterranea Cardioctr, Naples, Italy
关键词
D O I
10.1097/FJC.0000000000000946
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:159 / 161
页数:3
相关论文
共 12 条
[1]   Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease [J].
Abbate, Antonio ;
Toldo, Stefano ;
Marchetti, Carlo ;
Kron, Jordana ;
Van Tassell, Benjamin W. ;
Dinarello, Charles A. .
CIRCULATION RESEARCH, 2020, 126 (09) :1260-1280
[2]  
Deswal A, 2001, CIRCULATION, V103, P2055
[3]   Anti-Inflammatory Therapy With Canakinumab for the Prevention of Hospitalization for Heart Failure [J].
Everett, Brendan M. ;
Cornel, Jan H. ;
Lainscak, Mitja ;
Anker, Stefan D. ;
Abbate, Antonio ;
Thuren, Tom ;
Libby, Peter ;
Glynn, Robert J. ;
Ridker, Paul M. .
CIRCULATION, 2019, 139 (10) :1289-1299
[4]   Validation of a new score for outcome prediction in patients with heart failure with reduced ejection fraction [J].
Loiacono, Ferdinando ;
Fragasso, Gabriele ;
Calori, Giliola ;
Alberti, Luca ;
Marinosci, Giovanni ;
Salerno, Anna ;
Margonato, Alberto .
MINERVA CARDIOANGIOLOGICA, 2019, 67 (03) :191-199
[5]   Inflammation in Heart Failure JACC State-of-the-Art Review [J].
Murphy, Sean P. ;
Kakkar, Rahul ;
McCarthy, Cian P. ;
Januzzi, James L. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2020, 75 (11) :1324-1340
[6]   Cardiotrophin as a prognostic factor in heart failure [J].
Qawoq, Haval D. ;
Sobczak, Maria ;
Szczesniak, Piotr ;
Pagorek, Piotr ;
Miskowiec, Dawid ;
Wierzbowska Drabik, Karina ;
Chrzanowski, Lukasz ;
Kasprzak, Jaroslaw D. .
MINERVA CARDIOANGIOLOGICA, 2019, 67 (03) :258-260
[7]   The NLRP3 Inflammasome Inhibitor, OLT1177 (Dapansutrile), Reduces Infarct Size and Preserves Contractile Function After Ischemia Reperfusion Injury in the Mouse [J].
Toldo, Stefano ;
Mauro, Adolfo Gabriele ;
Cutter, Zachary ;
Van Tassel, Benjamin W. ;
Mezzaroma, Eleonora ;
Del Buono, Marco Giuseppe ;
Prestamburgo, Andrea ;
Potere, Nicola ;
Abbate, Antonio .
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2019, 73 (04) :215-222
[8]   Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the studies of left ventricular dysfunction (SOLVD) [J].
TorreAmione, G ;
Kapadia, S ;
Benedict, C ;
Oral, H ;
Young, JB ;
Mann, DL .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1996, 27 (05) :1201-1206
[9]   Usefulness of Canakinumab to Improve Exercise Capacity in Patients With Long-Term Systolic Heart Failure and Elevated C-Reactive Protein [J].
Trankle, Cory R. ;
Canada, Justin M. ;
Cei, Laura ;
Abouzaki, Nayef ;
Oddi-Erdle, Claudia ;
Kadariya, Dinesh ;
Christopher, Sanah ;
Viscusi, Michele ;
Del Buono, Marco ;
Kontos, Michael C. ;
Arena, Ross ;
Van Tassell, Benjamin ;
Abbate, Antonio .
AMERICAN JOURNAL OF CARDIOLOGY, 2018, 122 (08) :1366-1370
[10]   Interleukin-1 Blockade in Recently Decompensated Systolic Heart Failure Results From REDHART (Recently Decompensated Heart Failure Anakinra Response Trial) [J].
Van Tassell, Benjamin W. ;
Canada, Justin ;
Carbone, Salvatore ;
Trankle, Cory ;
Buckley, Leo ;
Erdle, Claudia Oddi ;
Abouzaki, Nayef A. ;
Dixon, Dave ;
Kadariya, Dinesh ;
Christopher, Sanah ;
Schatz, Aaron ;
Regan, Jessica ;
Viscusi, Michele ;
Del Buono, Marco ;
Melchior, Ryan ;
Mankad, Pranav ;
Lu, Juan ;
Sculthorpe, Robin ;
Biondi-Zoccai, Giuseppe ;
Lesnefsky, Edward ;
Arena, Ross ;
Abbate, Antonio .
CIRCULATION-HEART FAILURE, 2017, 10 (11)