A mild, efficient and general method for the synthesis of trialkylsilyl (Z)-4-oxo-2-alkenoates and γ-hydroxybutenolides

被引：45

作者：

Boukouvalas, J ^{[1
]}

Lachance, N ^{[1
]}

机构：

[1] Univ Laval, Dept Chim, Quebec City, PQ G1K 7P4, Canada

来源：

SYNLETT | 1998年 / 01期

关键词：

gamma-hydroxybutenolides; trialkylsilyl (Z)-4-oxo-2-alkenoates; 2-trialkylsilyloxyfurans; dimethyldioxirane; oxidation;

D O I：

10.1055/s-1998-1574

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Trialkylsilyloxyfurans react rapidly with dimethyldioxirane at -78 degrees C to provide trialkylsilyl (Z)-4-oxo-2-alkenoates whose hydrolysis delivers gamma-hydroxybutenolides with high efficiency; a short synthesis of a naturally occurring monoterpene gamma-hydroxybutenolide (4) is reported.

引用

页码：31 / +

页数：3

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