Ru-Catalyzed Selective C(sp3)-H Monoborylation of Amides and Esters

被引：14

作者：

Yao, Wubing ^{[1
]}

Yang, Jianguo ^{[1
]}

Hao, Feiyue ^{[1
]}

机构：

[1] Taizhou Univ, Sch Pharmaceut & Mat Engn, Jiaojiang 318000, Zhejiang, Peoples R China

来源：

CHEMSUSCHEM | 2020年 / 13卷 / 01期

基金：

中国博士后科学基金;

关键词：

amides; borylation; C-H activation; ester; ruthenium; BOND ACTIVATION; BORYLATION; CHEMISTRY; FUNCTIONALIZATION; DEHYDROGENATION; ORGANOBORANES; REAGENTS; HALIDES;

D O I：

10.1002/cssc.201902448

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A ruthenium-catalyzed method has been developed for the C(sp(3))-H monoborylation of various unactivated alkyl and aryl amides and challenging esters, with a low-cost and bench-stable boron source, providing boronates with exclusive selectivity, high efficiency, and high turnover number (up to 8900). This novel strategy may offer a versatile and environmentally friendly alternative to current methods for selective C(sp(3))-H borylation that employ even more expensive metals, such as iridium and rhodium.

引用

页码：121 / 125

页数：5

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