Granulocytic sarcoma, a diagnostic challenge: 3 pediatric cases

被引:6
作者
Renard, C. [1 ]
Girard, S. [2 ]
Pracros, J. P. [3 ]
Dijoud, F. [4 ]
Andre, J. -M. [1 ]
Mialou, V. [1 ]
Bertrand, Y. [1 ]
机构
[1] Inst Hematol & Oncol Pediat, F-69008 Lyon, France
[2] Hop Edouard Herriot, Serv Hematol Biol, F-69437 Lyon 03, France
[3] Hop Femme Mere Enfant, Serv Radiol Pediat, F-69677 Bron, France
[4] Ctr Biol & Pathol Est, F-69677 Bron, France
来源
ARCHIVES DE PEDIATRIE | 2010年 / 17卷 / 02期
关键词
ACUTE MYELOID-LEUKEMIA; EXTRAMEDULLARY LEUKEMIA; CHILDREN; INTUSSUSCEPTION; TUMORS;
D O I
10.1016/j.arcped.2009.10.018
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Ganulocytic sarcoma (GS) is a rare extramedullary tumor frequently associated with acute myeloblastic leukemia (AML). We report 3 cases of pediatric granulocyctic sarcomas with various locations: skin, orbit, and bowel. Cases 1 and 2 were associated with AML; case 3 was isolated. In all 3 cases, the diagnosis was delayed or initially missed. Pathology and immunohistochemistry data identified the disease. CS is treated with chemotherapy, like AML. The prognosis of GS seems better than that of isolated AML. (C) 2009 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:149 / 153
页数:5
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