The Role of the Gut Microbiota in the Development of Ischemic Stroke

被引：30

作者：

Wang, Jinchen ^{[1
,2
]}

Zhang, Hongfei ^{[1
]}

He, Jianying ^{[3
]}

Xiong, Xiaoxing ^{[2
]}

机构：

[1] Southern Med Univ, Dept Anesthesiol, Zhujiang Hosp, Guangzhou, Peoples R China

[2] Wuhan Univ, Cent Lab, Renmin Hosp, Wuhan, Peoples R China

[3] Nanchang Med Coll, Affiliated Hosp 1, JiangXi Prov Peoples Hosp, Dept Orthoped, Nanchang, Jiangxi, Peoples R China

来源：

FRONTIERS IN IMMUNOLOGY | 2022年 / 13卷

基金：

中国国家自然科学基金;

关键词：

ischemic stroke; gut microbiota; gut-brain axis communication; neuro inflammation; fecal microbiota transplantation; REGULATORY T-CELLS; CHAIN FATTY-ACIDS; INTESTINAL MICROBIOTA; SODIUM-BUTYRATE; NERVOUS-SYSTEM; BLOOD-PRESSURE; BRAIN; IMMUNE; DYSBIOSIS; RECEPTOR;

D O I：

10.3389/fimmu.2022.845243

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

An increasing number of studies have focused on the gut microbiota and its relationship with various neurological diseases. The gut microbiota can affect the metabolic status of the body, in addition to having an important impact on blood pressure, blood glucose, and atherosclerosis, all of which are risk factors for ischemic stroke. In this review, we summarized studies that included the physiological function of the gut microbiota and gut microbiota disorders related to the central nervous system, thus providing novel ideas for the prevention and treatment of ischemic stroke.

引用

页数：13

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