Higher sensitivity of denaturing gradient gel electrophoresis than sequencing in the detection of mutations in DNA from tumor samples

被引：20

作者：

García-Delgado, M ^{[1
]}

González-Navarro, CJ ^{[1
]}

Napal, CC ^{[1
]}

Baldonado, C ^{[1
]}

Vizmanos, JL ^{[1
]}

Gullón, A ^{[1
]}

机构：

[1] Univ Navarra, Fac Sci, Dept Genet, E-31080 Navarra, Spain

来源：

BIOTECHNIQUES | 1998年 / 24卷 / 01期

关键词：

D O I：

10.2144/98241bm15

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：72 / +

页数：3

共 12 条

[1] PROGNOSTIC-SIGNIFICANCE OF TP53 ALTERATIONS IN BREAST-CARCINOMA [J].

ANDERSEN, TI ;

HOLM, R ;

NESLAND, JM ;

HEIMDAL, KR ;

OTTESTAD, L ;

BORRESEN, AL .

BRITISH JOURNAL OF CANCER, 1993, 68 (03) :540-548

[2] ALTERATIONS OF THE TP53 GENE AS A POTENTIAL PROGNOSTIC MARKER IN BREAST CARCINOMAS - ADVANTAGES OF USING CONSTANT DENATURANT GEL-ELECTROPHORESIS IN MUTATION DETECTION [J].

ANDERSEN, TI ;

BORRESEN, AL .

DIAGNOSTIC MOLECULAR PATHOLOGY, 1995, 4 (03) :203-211

[3]

BECK JS, 1993, HUM GENET, V91, P25

[4]

BORRESEN AL, 1992, CANCER RES, V52, P3234

[5] CONSTANT DENATURANT GEL-ELECTROPHORESIS AS A RAPID SCREENING TECHNIQUE FOR P53 MUTATIONS [J].

BORRESEN, AL ;

HOVIG, E ;

SMITHSORENSEN, B ;

MALKIN, D ;

LYSTAD, S ;

ANDERSEN, TI ;

NESLAND, JM ;

ISSELBACHER, KJ ;

FRIEND, SH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (19) :8405-8409

[6]

BOSARI S, 1995, VIRCHOWS ARCH, V427, P229

[7]

CARBONE D, 1991, ONCOGENE, V6, P1691

[8]

HAMELIN R, 1993, ONCOGENE, V8, P2213

[9] POLYMERASE CHAIN REACTION-BASED METHODS FOR THE DETECTION OF MUTATIONS IN ONCOGENES AND TUMOR-SUPPRESSOR GENES [J].

LODA, M .

HUMAN PATHOLOGY, 1994, 25 (06) :564-571

[10]

LYNCH HT, 1981, GENETICS BREAST CANC

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