Lactobacillus spp. for Gastrointestinal Health: Current and Future Perspectives

被引:292
作者
Dempsey, Elaine [1 ,2 ]
Corr, Sinead C. [2 ,3 ]
机构
[1] Trinity Coll Dublin, Trinity Biomed Sci Inst, Sch Biochem & Immunol, Dublin, Ireland
[2] Trinity Coll Dublin, Moyne Inst Prevent Med, Sch Genet & Microbiol, Dept Microbiol, Dublin, Ireland
[3] Univ Coll Cork, APC Microbiome Ireland, Cork, Ireland
基金
爱尔兰科学基金会;
关键词
lactobacillus; probiotic; microbiota; gastrointestinal barrier; inflammation; HELICOBACTER-PYLORI ERADICATION; ANTIBIOTIC-ASSOCIATED DIARRHEA; CHAIN FATTY-ACIDS; INTESTINAL BARRIER FUNCTION; INFLAMMATORY-BOWEL-DISEASE; MUCIN GENE-EXPRESSION; ESCHERICHIA-COLI; JOHNSONII LA1; LACTIC-ACID; IN-VITRO;
D O I
10.3389/fimmu.2022.840245
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In recent decades, probiotic bacteria have become increasingly popular as a result of mounting scientific evidence to indicate their beneficial role in modulating human health. Although there is strong evidence associating various Lactobacillus probiotics to various health benefits, further research is needed, in particular to determine the various mechanisms by which probiotics may exert these effects and indeed to gauge inter-individual value one can expect from consuming these products. One must take into consideration the differences in individual and combination strains, and conditions which create difficulty in making direct comparisons. The aim of this paper is to review the current understanding of the means by which Lactobacillus species stand to benefit our gastrointestinal health.
引用
收藏
页数:15
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