Visible-Light-Mediated Direct Amidation of Arenes and Heteroarenes with N-Aminopyridinium Salts

被引：3

作者：

Xia, Cencen ^{[1
]}

Hao, Xinyu ^{[1
]}

Jin, Kun ^{[1
]}

Zhang, Rong ^{[1
]}

Duan, Chunying ^{[1
]}

Li, Yaming ^{[1
]}

机构：

[1] Dalian Univ Technol, Sch Chem Engn, State Key Lab Fine Chem, Dalian 116024, Liaoning, Peoples R China

来源：

SYNLETT | 2022年 / 33卷 / 15期

基金：

中国国家自然科学基金;

关键词：

photocatalysis; amidopyridinium salts; amidation; 3+2]-annulation; radical reactions; AMIDE BOND FORMATION; C-H AMIDATION; COUPLING REAGENTS; AMINOHYDROXYLATION; FUNCTIONALIZATION; INHIBITION; ALDEHYDES; OLEFINS; AMINES; CELL;

D O I：

10.1055/a-1867-7228

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel photoinduced strategy has been developed for the C-H amidation of aromatics and heteroaromatics by using benzamide radicals with free NH groups generated from N-amidopyridinium salts under visible-light irradiation. The new mode of activation of N-amidopyridinium salts proceeds efficiently under mild conditions to give various benzamide derivatives with free NH groups. In addition, oxazoline analogues, synthesized by the reaction with styrene, demonstrate a substantial range of prospective applications for this versatile protocol.

引用

收藏

页码：1551 / 1555

页数：5

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