Carbon nanomaterial;
Fullerene;
Nanotube;
Graphene;
Laser desorption/ionization;
Mass spectrometry;
MALDI-TOF-MS;
SOLID-PHASE EXTRACTION;
LOW-CONCENTRATION PEPTIDES;
REDUCED GRAPHENE OXIDE;
CHAIN FATTY-ACIDS;
SMALL MOLECULES;
DESORPTION-IONIZATION;
SELECTIVE ENRICHMENT;
HIGHLY EFFICIENT;
MAGNETIC GRAPHENE;
D O I:
10.1007/s00216-015-9255-4
中图分类号:
Q5 [生物化学];
学科分类号:
071010 ;
081704 ;
摘要:
Carbon nanomaterials have attracted great interest over past decades owing to their unique physical properties, versatile functionalization chemistry, and biological compatibility. In this article, we review recent progress in application of carbon nanomaterials in laser desorption/ionization mass spectrometry (LDI MS). Various types of carbon nanomaterials, including fullerenes, carbon nanotubes, graphene, carbon nanodots, nanodiamond, nanofibers, nanohorns, and their derivative forms, are involved. The applications of these materials as new matrices or probes in matrix-assisted or surface-enhanced laser desorption/ionization mass spectrometry (MALDI or SELDI MS) are discussed. Finally, we summarize current challenges and give our perspectives on the future of applications of carbon nanomaterials in LDI MS.
机构:
Univ Liege, Chem Dept, MolSys Res Unit, Mass Spectrometry Lab, Allee Six Aout,11 Quartier Agora, B-4000 Liege, BelgiumUniv Liege, Chem Dept, MolSys Res Unit, Mass Spectrometry Lab, Allee Six Aout,11 Quartier Agora, B-4000 Liege, Belgium
Mueller, Wendy H.
Verdin, Alexandre
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Univ Liege, Chem Dept, MolSys Res Unit, Mass Spectrometry Lab, Allee Six Aout,11 Quartier Agora, B-4000 Liege, BelgiumUniv Liege, Chem Dept, MolSys Res Unit, Mass Spectrometry Lab, Allee Six Aout,11 Quartier Agora, B-4000 Liege, Belgium
Verdin, Alexandre
De Pauw, Edwin
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Univ Liege, Chem Dept, MolSys Res Unit, Mass Spectrometry Lab, Allee Six Aout,11 Quartier Agora, B-4000 Liege, BelgiumUniv Liege, Chem Dept, MolSys Res Unit, Mass Spectrometry Lab, Allee Six Aout,11 Quartier Agora, B-4000 Liege, Belgium
De Pauw, Edwin
Malherbe, Cedric
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Univ Liege, Chem Dept, MolSys Res Unit, Mass Spectrometry Lab, Allee Six Aout,11 Quartier Agora, B-4000 Liege, BelgiumUniv Liege, Chem Dept, MolSys Res Unit, Mass Spectrometry Lab, Allee Six Aout,11 Quartier Agora, B-4000 Liege, Belgium
Malherbe, Cedric
Eppe, Gauthier
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Univ Liege, Chem Dept, MolSys Res Unit, Mass Spectrometry Lab, Allee Six Aout,11 Quartier Agora, B-4000 Liege, BelgiumUniv Liege, Chem Dept, MolSys Res Unit, Mass Spectrometry Lab, Allee Six Aout,11 Quartier Agora, B-4000 Liege, Belgium