Recent progress in application of carbon nanomaterials in laser desorption/ionization mass spectrometry

被引:52
|
作者
Wang, Jing [1 ]
Liu, Qian [1 ,2 ]
Liang, Yong [1 ]
Jiang, Guibin [1 ,2 ]
机构
[1] Jianghan Univ, Inst Environm & Hlth, Wuhan 430056, Peoples R China
[2] Chinese Acad Sci, State Key Lab Environm Chem & Ecotoxicol, Ecoenvironm Sci Res Ctr, Beijing 100085, Peoples R China
基金
中国国家自然科学基金;
关键词
Carbon nanomaterial; Fullerene; Nanotube; Graphene; Laser desorption/ionization; Mass spectrometry; MALDI-TOF-MS; SOLID-PHASE EXTRACTION; LOW-CONCENTRATION PEPTIDES; REDUCED GRAPHENE OXIDE; CHAIN FATTY-ACIDS; SMALL MOLECULES; DESORPTION-IONIZATION; SELECTIVE ENRICHMENT; HIGHLY EFFICIENT; MAGNETIC GRAPHENE;
D O I
10.1007/s00216-015-9255-4
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Carbon nanomaterials have attracted great interest over past decades owing to their unique physical properties, versatile functionalization chemistry, and biological compatibility. In this article, we review recent progress in application of carbon nanomaterials in laser desorption/ionization mass spectrometry (LDI MS). Various types of carbon nanomaterials, including fullerenes, carbon nanotubes, graphene, carbon nanodots, nanodiamond, nanofibers, nanohorns, and their derivative forms, are involved. The applications of these materials as new matrices or probes in matrix-assisted or surface-enhanced laser desorption/ionization mass spectrometry (MALDI or SELDI MS) are discussed. Finally, we summarize current challenges and give our perspectives on the future of applications of carbon nanomaterials in LDI MS.
引用
收藏
页码:2861 / 2873
页数:13
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