High HIV Positivity Rates Following Large-Scale HIV Self-Testing Implementation in Zimbabwe, 2018-2020

被引:3
作者
Muchedzi, Auxilia [1 ]
Mpofu, Mulamuli [2 ]
Mudzengerere, Fungai H. [1 ]
Bateganya, Moses [3 ]
Mavimba, Tarirai [1 ]
Satti, Hind [3 ]
Dhliwayo, Rumbidzai [1 ]
Zulu, Tinashe [1 ]
Tapera, Talent [1 ]
Samushonga, Tendai [1 ]
Nyagura, Tendai [4 ]
Ncube, Getrude [5 ]
Tafuma, Taurayi A. [1 ]
机构
[1] FHI 360, Harare, Zimbabwe
[2] FHI 360, Gaborone, Botswana
[3] FHI 360, Durham, NC USA
[4] United States Agcy Int Dev USAID, Harare, Zimbabwe
[5] Minist Hlth & Child Care, Harare, Zimbabwe
关键词
Zimbabwe; HIV; self-testing; Sub-Saharan Africa; HIV testing;
D O I
10.3389/fpubh.2021.606376
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Introduction: HIV self-testing (HIV-ST) is an innovative strategy to increase HIV case identification. This analysis shares the outcomes of HIV-ST implementation within the Zimbabwe HIV Care and Treatment (ZHCT) project for the period October 2018-March, 2020. Materials and Methods: We extracted HIV-ST data for the period October 2018 to March 2020 from the project database and assessed (1) the proportion of reactive HIV-ST results; (2) the concordance between reactive HIV-ST results against rapid confirmatory HIV tests using Determine (TM) and Chembio (TM) in parallel; and (3) the monthly contribution of HIV-ST to total HIV positive individuals identified within project. The Chi-square test was used to assess for statistical differences in HIV positivity between age groups, by sex and district; as well as the difference in HIV positivity between the HIV-ST and index and mobile testing strategies. Findings: Between October 2018 and March 2020, the ZHCT project distributed 11,983 HIV-ST kits; 11,924 (99.8%) were used and 2,616 (21.9%) were reactive. Of the reactive tests, 2,610 (99.8%) were confirmed HIV positive giving a final positivity rate of 21.9%, and a concordance rate of 99.8% between the HIV-ST results and the confirmatory tests. Proportion of reactive results differed by age-groups (p < 0.001); with the 35-49 years having the highest positivity rate of 25.5%. The contribution of HIV-ST to total new positives increased from 10% in October 2018 to 80% at the end of March 2020 (p < 0.001). Positivity rates from HIV-ST were significantly different by age-groups, sex and district (p = 0.04). Additionally, index and mobile testing had a higher positivity rate compared to HIV-ST (p < 0.001). Conclusion: The ZHCT project has successfully scaled up HIV self-testing which contributed significantly to HIV case finding. Countries should consider using the lessons to scale-up the intervention which will contribute in reaching under-served and undiagnosed populations.
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页数:9
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