Hepcidin and iron metabolism

被引：4
|
作者：
Delaby, C.
Deybach, J.-C.
Beaumont, C.
机构：
[1] Univ Paris 07, Ctr Rech Biomed Bichat Beaujon CRB3, INSERM, U773, F-75870 Paris, France
[2] Hop Louis Mourier, Ctr Francis Porphyries, APHP, F-92701 Colombes, France
来源：
REVUE DE MEDECINE INTERNE | 2007年 / 28卷 / 07期
关键词：
iron; hepcidin; hemochromatosis; anemia of chronic disease (ACD);
D O I：
10.1016/j.revmed.2007.03.009
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Introduction. - In mammals, iron balance is maintained by regulating intestinal iron absorption and iron recycling by macrophages. Exegesis. - The central role of hepcidin in the establishment of iron deficiency or overload has been revealed by the study of murine models. Conclusion. - Many hopes have emerged from the discovery of hepcidin, pointing to potential treatments for hemochromatosis and anemia of inflammation (anemia of chronic disease). (C) 2007 Elsevier Masson SAS. Tous droits reserves.
引用
收藏
页码：510 / 512
页数：3
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