Transformation of triclosan by Trametes versicolor and Pycnoporus cinnabarinus

被引：78
作者：
Hundt, K
Martin, D
Hammer, E
Jonas, U
Kindermann, MK
Schauer, F
机构：
[1] Ernst Moritz Arndt Univ Greifswald, Inst Microbiol & Mol Biol, D-17487 Greifswald, Germany
[2] Ernst Moritz Arndt Univ Greifswald, Inst Chem & Biochem, D-17487 Greifswald, Germany
[3] Sudzucker AG Mannheim, Ochsenfurt, ZAFES, D-67283 Obrigheim, Germany
来源：
APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2000年 / 66卷 / 09期
关键词：
D O I：
10.1128/AEM.66.9.4157-4160.2000
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
We investigated the ability of Trametes versicolor and Pycnoporous cinnabarinus to metabolize triclosan. T. versicolor produced three metabolites, 2-O-(2,4,4'-trichlorodiphenyl ether)-beta-D-xylopyranoside, 2-O-(2,4,4'-trichlorodiphenyl ether)-beta-D-glucopyranoside, and 2,4-dichlorophenol. P. cinnabarinus converted triclosan to 2,2,4'-trichloro-2'-methoxydiphenyl ether and the glucoside conjugate known from T. versicolor. The conjugates showed a distinctly lower cytotoxic and microbicidal activity than triclosan did.
引用
收藏
页码：4157 / 4160
页数：4
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