The Virtual Family-development of surface-based anatomical models of two adults and two children for dosimetric simulations

被引:1123
作者
Christ, Andreas [1 ]
Kainz, Wolfgang [2 ]
Hahn, Eckhart G. [3 ]
Honegger, Katharina [1 ]
Zefferer, Marcel [1 ]
Neufeld, Esra [1 ,4 ]
Rascher, Wolfgang [3 ]
Janka, Rolf [3 ]
Bautz, Werner [3 ]
Chen, Ji [5 ]
Kiefer, Berthold [6 ]
Schmitt, Peter [6 ]
Hollenbach, Hans-Peter [6 ]
Shen, Jianxiang [5 ]
Oberle, Michael [1 ]
Szczerba, Dominik [1 ]
Kam, Anthony [7 ]
Guag, Joshua W. [2 ]
Kuster, Niels [1 ,4 ]
机构
[1] Fdn Res Informat Technol Soc ITIS, CH-8004 Zurich, Switzerland
[2] US FDA, CDRH, Silver Spring, MD 20993 USA
[3] Univ Erlangen Nurnberg, Univ Klinikum Erlangen, D-91054 Erlangen, Germany
[4] Swiss Fed Inst Technol ETHZ, CH-8092 Zurich, Switzerland
[5] Univ Houston, Dept Elect & Comp Engn, Houston, TX 77204 USA
[6] Siemens Healthcare, MR Applicat Dev, D-91052 Erlangen, Germany
[7] Johns Hopkins Bayview Med Ctr, Dept Imaging, Baltimore, MD 21224 USA
关键词
BODY-MASS INDEX; ELECTROMAGNETIC-FIELDS; FREQUENCY-RANGE; HUMAN HEAD; ABSORPTION; TISSUES; SAR; SEGMENTATION; PHANTOMS; EXPOSURE;
D O I
10.1088/0031-9155/55/2/N01
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The objective of this study was to develop anatomically correct whole body human models of an adult male (34 years old), an adult female (26 years old) and two children (an 11-year-old girl and a six-year-old boy) for the optimized evaluation of electromagnetic exposure. These four models are referred to as the Virtual Family. They are based on high resolution magnetic resonance (MR) images of healthy volunteers. More than 80 different tissue types were distinguished during the segmentation. To improve the accuracy and the effectiveness of the segmentation, a novel semi-automated tool was used to analyze and segment the data. All tissues and organs were reconstructed as three-dimensional (3D) unstructured triangulated surface objects, yielding high precision images of individual features of the body. This greatly enhances the meshing flexibility and the accuracy with respect to thin tissue layers and small organs in comparison with the traditional voxel-based representation of anatomical models. Conformal computational techniques were also applied. The techniques and tools developed in this study can be used to more effectively develop future models and further improve the accuracy of the models for various applications. For research purposes, the four models are provided for free to the scientific community.
引用
收藏
页码:N23 / N38
页数:16
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