A facile route to diastereomerically pure analogues of castanospermine and australine.

被引：19

作者：

Marek, D

Wadouachi, A

Uzan, R

Beaupere, D

Nowogrocki, G

Laplace, G

机构：

[1] UNIV PICARDIE,CHIM ORGAN LAB,F-80039 AMIENS,FRANCE

[2] ENSC,LAB CRISTALLOCHIM & PHYSICOCHIM SOLIDE,F-59652 VILLENEUVE DASCQ,FRANCE

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 01期

关键词：

D O I：

10.1016/0040-4039(95)02093-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of cysteamine with D-ribofuranose in which a 2,3-O-isopropylidene group was introduced, yielded the 2-(S)-thiazolidine derivative stereoselectively. The following step of cyclisation led to castanospermine and australine analogues, 3 and 4, in good yields. It was shown that the ratio castanospermine/australine analogues was depending on the activating reagent used for the cyclisation step.

引用

页码：49 / 52

页数：4

共 14 条

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