The Ag-promoted α-C-H arylation of alcohols

被引：12

作者：

Wang, Shoufeng ^{[1
,2
]}

Xing, Shuya ^{[1
]}

Zhang, Yingying ^{[1
]}

Fan, Yafei ^{[1
,2
]}

Zhao, Huaiqing ^{[1
,3
]}

Wang, Jianfeng ^{[4
]}

Zhang, Shuxiang ^{[1
,2
]}

Wang, Wengui ^{[1
,2
]}

机构：

[1] Univ Jinan, Sch Chem & Chem Engn, 336 West Rd Nan Xinzhuang, Jinan 250022, Shandong, Peoples R China

[2] Shandong Prov Key Lab Fluorine Chem & Chem Mat, 336 West Rd Nan Xinzhuang, Jinan 250022, Shandong, Peoples R China

[3] Key Lab Inteifacial React & Sensing Anal Univ Sha, 336 West Rd Nan Xinzhuang, Jinan 250022, Shandong, Peoples R China

[4] Hangzhou Normal Univ, Affiliated Hosp, Dept Resp Dis, Hangzhou 310015, Zhejiang, Peoples R China

来源：

RSC ADVANCES | 2019年 / 9卷 / 71期

关键词：

BOND FORMATION; COUPLING REACTION; FUNCTIONALIZATION; ALKENES; ETHERS;

D O I：

10.1039/c9ra09954a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We herein report the functionalization of alpha-C-H in alcohols through cross-dehydrogenative coupling reactions. Selectfluor was used as a mild oxidant. In situ-generated HF participated in the reaction and no external strong acid was necessary. A variety of heteroaryl-substituted alcohols were achieved with good yields and with good functional group tolerance.

引用

页码：41847 / 41850

页数：4

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