Advancing early gastric cancer detection

被引：13

作者：

Gillen, Sarah ^{[1
]}

机构：

[1] Beatson Inst Canc Res, Garscube Estate Switchback Rd Bearsden, Glasgow G61 1BD, Scotland

来源：

FEBS OPEN BIO | 2021年 / 11卷 / 07期

关键词：

biomarker; gastric cancer; miRNA; miR-194; prognosis; the cancer genome atlas;

D O I：

10.1002/2211-5463.13217

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Important factors in combating cancer are early detection and accurate assessment of the best course of treatment. In a study published in this issue, Wang et al. identify possible miRNA biomarkers for improved determination of gastric cancer stage and prognosis. In particular, they show increased miR-194 levels are a predictor of more favourable gastric cancer prognosis, at least in part due to miR-194 downregulating production of a key protein for cancer development: CCND1.

引用

页码：1812 / 1813

页数：2

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