Microarray analysis of gene expression profiles in the bovine mammary gland during lactation

被引：12

作者：

Hou XiaoMing ^{[1
]}

Li QingZhang ^{[1
]}

Huang TianYing ^{[1
]}

机构：

[1] NE Agr Univ, Key Lab Dairy Sci, Educ Minist, Harbin 150030, Peoples R China

来源：

SCIENCE CHINA-LIFE SCIENCES | 2010年 / 53卷 / 02期

基金：

国家高技术研究发展计划(863计划);

关键词：

mammary gland; microarray; lactation; genomics; gene expression profile; INCREASED MILKING FREQUENCY; EPITHELIAL-CELLS; SECRETION; INVOLUTION; PREGNANCY; TISSUE;

D O I：

10.1007/s11427-010-0034-3

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Mammary glands undergo functional and metabolic changes during virgin, lactation and dry periods. A total of 122 genes were identified as differentially expressed, including 79 up-regulated and 43 down-regulated genes during lactation compared with virgin and dry periods. Gene ontology analysis showed the functional classification of the up-regulated genes in lactation, including transport, biosynthetic process, signal transduction, catalytic activity, immune system process, cell death, and positive regulation of the developmental process. Microarray data clarified molecular events in bovine mammary gland lactation.

引用

页码：248 / 256

页数：9

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