Deacylation studies on furanose triesters using an immobilized lipase: Synthesis of a key precursor for bicyclonucleosides

被引：23

作者：

Prasad, Ashok K. ^{[1
]}

Kalra, Neerja

Yadav, Yogesh

Kumar, Rajesh

Sharma, Sunil K.

Patkar, Shamkant

Lange, Lene

Wengel, Jesper

Parmar, Virinder S.

机构：

[1] Univ Delhi, Dept Chem, Bioorgan Lab, Delhi 110007, India

[2] Univ So Denmark, Dept Chem, DK-5230 Odense M, Denmark

[3] Novozymes AS, DK-2880 Bagsvaerd, Denmark

来源：

CHEMICAL COMMUNICATIONS | 2007年 / 25期

关键词：

D O I：

10.1039/b618426j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Lipozyme(R) TL IM immobilized on silica catalyses the deacylation of 4-C-acyloxymethyl-3,5-di-O-acyl-1,2-O-(1-methylethylidene)-beta-L-threo-pentofuranose to form 3,5-di-O-acyl-4-C-hydroxymethyl-1,2-O-(1-methylethylidene)-alpha-D-xylo-pentofuranose in a highly selective and efficient manner.

引用

页码：2616 / 2617

页数：2

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