Activity of antioxidant enzymes in the skin during surgical wounds

被引：21
|
作者：
Mikhal'chik, E. V. [1 ]
Anurov, M. V. [1 ]
Titkova, S. M. [1 ]
Miroshnikova, E. A. [1 ]
Lukasheva, E. V. [1 ]
Deeva, I. B. [1 ]
Ibragimova, G. A. [1 ]
Korkina, L. G. [1 ]
机构：
[1] Russian State Med Univ, Russian Univ Peoples Friendship, Moscow 117437, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2006年 / 142卷 / 06期
关键词：
wounds; skin; antioxidant enzymes; myeloperoxidase;
D O I：
10.1007/s10517-006-0446-z
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Full-thickness skin wounds (460 mm(2)) in rats were associated with increased blood chemiluminescence and neutrophil infiltration of the wound tissue and surrounding skin (recorded by myeloperoxidase activity). Activities of glutathione peroxidase and glutathione S-transferase in the skin and wound tissue increased on days 4 and 8. A correlation was revealed between activities of these enzymes and myeloperoxidase activity. Activities of myeloperoxidase and catalase increased in patient's skin excised during plastic surgeries of more than 2.5 h duration.
引用
收藏
页码：667 / 669
页数：3
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