Current Progress on Biosensors and Point-of-Care Devices for Sepsis Diagnosis

被引：7

作者：

Tsounidi, Dimitra ^{[1
]}

Petrou, Panagiota S. ^{[1
]}

Raptis, Ioannis ^{[2
]}

机构：

[1] Natl Ctr Sci Res Demokritos, Inst Nucl & Radiol Sci & Technol Energy & Safety, Immunoassay Immunosensors Lab, Aghia Paraskevi 15341, Greece

[2] Natl Ctr Sci Res Demokritos, Inst Nanosci & Nanotechnol, Aghia Paraskevi 15341, Greece

来源：

IEEE SENSORS JOURNAL | 2021年 / 21卷 / 11期

关键词：

Biosensors; Biomarkers; Immune system; Electrodes; Diseases; Proteins; Prognostics and health management; electrochemical; point-of-care systems; optical; sepsis; sepsis biomarkers; C-REACTIVE PROTEIN; ON-A-CHIP; ELECTROCHEMICAL BIOSENSORS; NEONATAL SEPSIS; MOLECULAR DIAGNOSTICS; SENSITIVE DETECTION; TNF-ALPHA; BIOMARKERS; LABEL; PROCALCITONIN;

D O I：

10.1109/JSEN.2021.3050887

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Sepsis is a life-threatening syndrome that remains one of the major causes of mortality in critically ill patients worldwide. Early sepsis diagnosis is vital to prevent the disease progress and increase recovery chances through an appropriate antibiotic treatment. The need for specific and fast diagnosis has resulted to the development of bioanalytical approaches that could be used at the point-of-care (PoC). To this direction, different types of biosensors have been developed for detection and quantitative determination of one or more biomarkers related to sepsis diagnosis and prognosis. In this review, we provide an overview of the recent advancements in biosensors and PoC systems for sepsis diagnosis as well as a short introduction about the biomarkers currently implemented in sepsis diagnosis/prognosis. In addition, the conventional methods for sepsis diagnosis are presented in brief and a comparison with biosensors and point-of-care systems is provided.

引用

页码：12840 / 12855

页数：16

共 143 条

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