Amaranth leaf extract protects against hydrogen peroxide induced oxidative stress in Drosophila melanogaster

被引：7
|
作者：
Johnmark, Ndinawe [1 ]
Kinyi, Hellen W. [2 ]
机构：
[1] Kampala Int Univ, Sch Pharm, Kampala, Uganda
[2] Kabale Univ, Sch Med, Dept Biochem, Kabale, Uganda
来源：
BMC RESEARCH NOTES | 2021年 / 14卷 / 01期
关键词：
Oxidative stress; Amaranths; Drosophila melanogaster; Antioxidants; ANTIOXIDANT ACTIVITY;
D O I：
10.1186/s13104-021-05603-x
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Objective Amaranths leaves are rich in ascorbic acid and polyphenol compounds which have antioxidant activity. The aim of this study was to evaluate their in vivo antioxidant activity. The effect of consumption of Amaranth leaf extract on in vivo antioxidant activity, catalase enzyme activity and H2O2 induced oxidative stress in Drosophila melanogaster flies was assessed. Results Consumption of Amaranth leaf extract was associated with increased survival on exposure to H(2)o(2) in a dose dependent manner in Drosophila melanogaster flies. The study concludes that the ethanolic extract of Amaranth leaves offer protection against hydrogen peroxide-induced oxidative stress.
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页数：5
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