Endometrial adenocarcinoma associated with subtle lymph-vascular space invasion and lymph node metastasis: A histologic pattern mimicking intravascular and sinusoidal histiocytes
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作者:
McKenney, JK
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Stanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USAStanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USA
McKenney, JK
[1
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Kong, CS
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Stanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USAStanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USA
Kong, CS
[1
]
Longacre, TA
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Stanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USAStanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USA
Longacre, TA
[1
]
机构:
[1] Stanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USA
Lymph-vascular space invasion has been established as an independent prognostic factor in endometrial adenocarcinoma. Despite the importance of its recognition, the histologic patterns of lymph-vascular space involvement have not been well addressed in the surgical pathology literature. We report three cases of endometrioid adenocarcinoma of the uterine corpus associated with a subtle pattern of lymph-vascular space invasion closely mimicking intravascular histiocytes. Two cases had regional lymph node metastases composed of morphologically similar cells.