History, Evolution, and Importance of Emergency Endovascular Treatment of Acute Ischemic Stroke

被引：14

作者：

Holodinsky, Jessalyn K. ^{[1
]}

Yu, Amy Y. X. ^{[1
,2
,3
]}

Assis, Zarina A. ^{[4
]}

Al Sultan, Abdulaziz S. ^{[1
,3
]}

Menon, Bijoy K. ^{[1
,2
,3
,4
,5
]}

Demchuk, Andrew M. ^{[2
,3
,4
,5
]}

Goyal, Mayank ^{[2
,3
,4
,5
]}

Hill, Michael D. ^{[1
,2
,3
,4
,5
,6
]}

机构：

[1] Univ Calgary, Dept Community Hlth Sci, Cumming Sch Med, Hlth Sci Ctr, HBA 2935D,3300 Hosp Dr NW, Calgary, AB T2N 4N1, Canada

[2] Univ Calgary, Cumming Sch Med, Calgary Stroke Program, Calgary, AB, Canada

[3] Univ Calgary, Cumming Sch Med, Dept Clin Neurosci, Calgary, AB, Canada

[4] Univ Calgary, Cumming Sch Med, Dept Radiol, Calgary, AB, Canada

[5] Univ Calgary, Cumming Sch Med, Hotchkiss Brain Inst, Calgary, AB, Canada

[6] Univ Calgary, Cumming Sch Med, Dept Med, Calgary, AB, Canada

来源：

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS | 2016年 / 16卷 / 05期

关键词：

Ischemic stroke; Endovascular techniques; Thrombectomy; Reperfusion; Thrombolytic therapy; TISSUE-PLASMINOGEN-ACTIVATOR; TRANS-LUMINAL ANGIOPLASTY; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; HEALTH-CARE PROFESSIONALS; INTRAVENOUS T-PA; RANDOMIZED-TRIAL; INTRAARTERIAL THROMBOLYSIS; INTERVENTIONAL MANAGEMENT; ANGIOGRAPHIC REPERFUSION; MECHANICAL THROMBECTOMY;

D O I：

10.1007/s11910-016-0646-5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

More than 800,000 people in North America suffer a stroke each year, with ischemic stroke making up the majority of these cases. The outcomes of ischemic stroke range from complete functional and cognitive recovery to severe disability and death; outcome is strongly associated with timely re-perfusion treatment. Historically, ischemic stroke has been treated with intravenous thrombolytic agents with moderate success. However, five recently published positive trials have established the efficacy of endovascular treatment in acute ischemic stroke. In this review, we will discuss the history of stroke treatments moving from various intravenous thrombolytic drugs to intra-arterial thrombolysis, early mechanical thrombectomy devices, and finally modern endovascular devices. Early endovascular therapy failures, recent successes, and implications for current ischemic stroke management and future research directions are discussed.

引用

页数：14

共 103 条

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